Results 61 to 70 of about 27,872 (309)

Wind Tunnel Experimental Study of Lift Enhancement and Drag Reduction on a Swept Wing Based on a Co-Flow Jet Technique

open access: yesApplied Sciences
Co-flow jet (CFJ) is an active flow control technique that significantly enhances aerodynamic performance metrics such as the maximum lift and maximum lift-to-drag ratio of airfoils or wings.
Bo Wang   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

NUMERICAL SIMULATION ON REAR SPOILER ANGLE OF MINI MPV CAR FOR CONDUCTING STABILITY AND SAFETY

open access: yesJurnal Ilmiah SINERGI, 2019
Spoiler attached on the rear part of a car can generate drag force and negative lift force, called downforce. This drag force can increase air resistance to the car, meanwhile, a negative lift force can improve the car’s stability and safety.
Alief Avicenna Luthfie   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Effect of Stall Strip Position, Size and Geometry on the Lift Coefficient of NACA 001 Aerofoil [PDF]

open access: yes, 2017
This study aims to determine the optimum position and geometry of stall strips (SS) to control sudden fall of lift in wind turbine blades. The type of airfoil used in this study is NACA 0015 with 150 mm of chord length.
Shukrie Ahmmad   +13 more
core   +3 more sources

Application of Convolutional Neural Network to Predict Airfoil Lift Coefficient [PDF]

open access: yes2018 AIAA/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference, 2018
The adaptability of the convolutional neural network (CNN) technique for aerodynamic meta-modeling tasks is probed in this work. The primary objective is to develop suitable CNN architecture for variable flow conditions and object geometry, in addition to identifying a sufficient data preparation process.
Yao Zhang, WoongJe Sung, Dimitri Mavris
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Lift Coefficient Predictions for Delta Wing Under Pitching Motions

open access: yes, 2002
An analytic prediction method is presented to estimate the lift coefficient of delta wings under pitching motions. The method is based on the leading edge suction analogy, with regards to the dynamic effect resulting in the unsteady behaviour.
Christopher Jouannet   +3 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy