Results 81 to 90 of about 22,309 (312)
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Effect of Gurney Flap Geometry on a S809 Airfoil
International Journal of Aerospace Engineering, 2019 In this paper, the effect of Gurney flap shapes on wind turbine blade airfoil S809 has been studied by numerical simulation. First, the O-type grid is used in the numerical simulation. By comparing with experimental data, such as the lift force, the drag
Li-Shu Hao, Yong-Wei Gao
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Effect of Airfoil Wavy Surface on Aero Dynamic Coefficients [PDF]
فناوری در مهندسی هوافضا, 2018 Nowadays, with regard to the new methods of simulation, the designof airfoils have greatly changed and this allows the evaluation of the effect of various factors on the efficacy of airfoils.
Fahemeh Moazzami +2 more
doaj
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
A study on aerodynamic characteristics and visualization of flow field of lift-drag combined starter
Advances in Mechanical Engineering, 2019 This study refers to the modification of the aerodynamic characteristics of the starter for the lift-type vertical axis wind turbine, the structure of the traditional drag starter was improved, and the lift-drag combined starter model was proposed. Based
Fang Feng +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Parametric analysis of aerodynamic-propulsion integratedperformance for hypersonic vehicles
Kongqi donglixue xuebaoTo parametrically assess the aerodynamic-propulsion integrated performance of air-breathing hypersonic vehicles and comprehensively elucidate the influence rules of overall vehicle parameters on their performance, this paper proposes a parametric ...
Jingfan Chen, Xiaoqiang Fan, Bing Xiong
doaj +1 more source