Results 71 to 80 of about 20,457 (265)

Effect of canard-chordwise blowing on the aerodynamic characteristics of blended wing body aircraft

open access: yesXibei Gongye Daxue Xuebao
To enhance the effect of the canard increasing lift and pitching moment coefficient of the blended-wing-body(BWB) aircraft, numerical simulation is adopted to analyze the effect of the canard-chordwise blowing on the low-speed aerodynamic characteristics
YUAN Changyun   +5 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Measuring method of drag coefficient, lift coefficient and equivalent roughness of revetment block

open access: yesPROCEEDINGS OF HYDRAULIC ENGINEERING, 2000
This study examines measuring methods of drag coefficient, lift coefficient and equivalent roughness that are necessary for mechanical design of revetment blocks set on river banks. The setting method of blocks and the influence of the Reynolds number on drag force and lift force are examined by checking the experimental results.
YAMAMOTO, Kouichi   +6 more
openaire   +2 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

NUMERICAL SIMULATION OF FLOW ROUND FREE SPANNING SUBMARINE PIPELINE AT HIGH REYNOLDS NUMBER

open access: yesJixie qiangdu, 2018
Free spanning submarine pipeline work in the harsh condition and has many failure modes. Vortex-induced vibration is a significant cause leading to its fatigue failure.
HU Qin   +3 more
doaj  

Aerodynamic Analysis of Rigid Wing Sail Based on CFD Simulation for the Design of High-Performance Unmanned Sailboats

open access: yesMathematics
The utilization of unmanned sailboats as a burgeoning instrument for ocean exploration and monitoring is steadily rising. In this study, a dual sail configuration is put forth to augment the sailboats’ proficiency in its wind-catching ability and adapt ...
Shipeng Fang   +6 more
doaj   +1 more source

LIFT AND DRAG COEFFICIENTS FOR DIFFERENT MAGNUS ROTOR TYPES

open access: yesJournal of Energy Technology
In this paper, the results of numerical simulations for various Magnus rotor configurations are presented. For each configuration, a blocked structured mesh was designed in ICEM CFD. Numerical simulations were conducted using Ansys CFX. The influence of the aspect ratio on the lift and drag coefficients depending on the speed ratio was investigated, as
openaire   +2 more sources

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

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