Results 171 to 180 of about 1,177,346 (315)

Photoactivatable Ru(ii) polypyridyl complexes as dual action modulators of amyloid-beta peptide aggregation and Cu redox cycling. [PDF]

Chem Sci
Leech G, Acosta AL, Mahato S, Barrett PC, Hodges RO, McFarland SA, Storr T.   +6 more
europepmc   +1 more source

A Sacrificial 3D Printed Vessel‐on‐Chip Demonstrates a Versatile Approach to Model Granulation Tissue

Advanced Healthcare Materials, EarlyView.
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger, Phil Berger, Andrew I. Morrison, Hendrik Erfurth, Maria Thon, Eva‐Maria Dehne, Susan Gibbs, Jasper J. Koning   +7 more
wiley   +1 more source

Combined Metal-Metal and Metal-Ligand Cooperativity in Dicopper-Catalyzed Azide-Alkyne Cycloaddition Reactions. [PDF]

Organometallics
van Beek CB, Choi H, Hilberts MLA, Lammertink MM, Park B, Lutz M, Baik MH, Broere DLJ.   +7 more
europepmc   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Evaluating the pentapharmacological potency of otamixaban against lung cancer CDK2, transferase, oxidoreductase and signalling proteins. [PDF]

PLoS One
Baeissa HM, Bakhsh T, Shakoori AM, Sindi G, Zaki RM, Kamal MA, Alsufyani HA, Habib AH, Ishaq A Khayyat A, Rafeeq M, Jairajpuri DS.   +10 more
europepmc   +1 more source

Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology

Advanced Healthcare Materials, EarlyView.
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley   +1 more source

Asymmetric Dynamics Between the Protomers of the σ2 Receptor Homodimer. [PDF]

J Chem Inf Model
Xu M, Alyemni S, Borin VA, Majumder R, Nucci NV, Keck T, Frankowski K, Agarwal PK, Haider S.   +8 more
europepmc   +1 more source

Determinants of ligand binding affinity and cooperativity at the GLUT1 endofacial site.

Biochemistry, 2011
Trista K. Robichaud, A. Appleyard, R. Herbert, P. Henderson, A. Carruthers   +4 more
semanticscholar   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source

Cryo-EM ligand building using AlphaFold3-like model and molecular dynamics. [PDF]

PLoS Comput Biol
Haloi N, Howard RJ, Lindahl E.
europepmc   +1 more source