Results 201 to 210 of about 1,177,346 (315)

From fragments to follow-ups: rapid hit expansion by making use of EU-OPENSCREEN resources. [PDF]

RSC Med Chem
Benz LS, Wollenhaupt J, Jirgensons A, Miletic T, Mueller U, Weiss MS.   +5 more
europepmc   +1 more source

Mechanochemistry for Metal–Organic Frameworks and Covalent–Organic Frameworks (MOFs, COFs): Methods, Materials, and Mechanisms

Advanced Materials, EarlyView.
An overview is provided of the mechanochemistry of metal‐organic frameworks (MOFs) and covalent‐organic frameworks (COFs), highlighting opportunities and strategies for discovery, synthesis and reactivity studies of these materials. Mechanistic studies and comparisons to the mechanochemistry of organic solids are outlined, showcasing how advances in ...
Joseph M. Marrett, Farshid Effaty, Xavier Ottenwaelder, Tomislav Friščić   +3 more
wiley   +1 more source

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

Advanced Materials, EarlyView.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal, Sandra Clara‐Trujillo, Elena Lucena‐Sánchez, Francisco J. Hicke, Andrea Escudero, Sandra Pradana‐López, Nelia Jiménez‐Alduan, Paula Díez, Alba García‐Fernández, Ramón Martínez‐Máñez   +9 more
wiley   +1 more source

Investigating Metal and Fluorophore Controlled Intracellular Localization in Noble Metal Thiosemicarbazone Complexes. [PDF]

Chemistry
Sheernaly N, Steinbrueck A, Krahn N, Rumancev C, Peeters F, Jusufagic L, Ochs J, Garrevoet J, Falkenberg G, Rosenhahn A, Metzler-Nolte N.   +10 more
europepmc   +1 more source

Gradients of Aliveness and Engineering: A Taxonomy of Fungal Engineered Living Materials

Advanced Materials, EarlyView.
This paper explores the potential of fungal engineered living materials (ELMs), examining fungal biology and growth mechanisms, which underpin their development. It presents a classification framework based on aliveness, scaffold composition, and engineering degree. Unique properties such as self‐healing, biosensing, and bioremediation are highlighted,
Elise Elsacker, Jara Saluena Martin, Annah‐Ololade Sangosanya, Anouk Verstuyft, Aurélie Van Wylick, Eveline Peeters   +5 more
wiley   +1 more source

Nanobody-drug conjugates for targeting specific GPCR pairs. [PDF]

PLoS Biol
Huang X, Roth BL.
europepmc   +1 more source

Polyphenol‐Mediated Engineering of Lipid Nanoparticles With Crystalline Mesophases

Advanced Materials, EarlyView.
A polyphenol‐mediated strategy enables the one‐step formation of lipid nanoparticles with nonlamellar mesophases, including micellar cubic and hexagonal structures. These highly ordered nanostructures accommodate a wide range of cargos—from metal ions to mRNA—and offer a modular and versatile platform for constructing functional lipid‐based delivery ...
Shiyao Li, Patrick Charchar, Haitao Yu, Zhixing Lin, Hamish G. Brown, Wanjun Xu, Chan‐Jin Kim, Irene Yarovsky, Yi Ju, Frank Caruso   +9 more
wiley   +1 more source

Light‐Activated Micromotors in Air Propelled by Thermal Convection

Advanced Materials, EarlyView.
Near‐infrared‐driven micromotors in air can overcome gravity and generate convective motion by a light‐induced thermal mechanism driven by a temperature gradient in the air caused by the interaction of the gold nanoparticles present on the surface of ZnO and NIR irradiation.
Pedro Mena‐Giraldo, Gabrielle A. Mandl, Victor Quezada‐Novoa, Camilo Garcia‐Henao, Nicolas Bondon, Melanie Jane Hazlett, John A. Capobianco   +6 more
wiley   +1 more source

Roles of Hydration in Protein-Ligand Binding: Passive or Active Participant? [PDF]

J Phys Chem A
Evans KA, Sun HM, Powers M, Lantz C, Laganowsky A, Rye H, Russell DH.   +6 more
europepmc   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

Advanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou, Isabel B. Hui, Carla Fernandez‐Rico, Marcy Zenobi‐Wong   +3 more
wiley   +1 more source