Results 211 to 220 of about 363,417 (316)

Intramolecular sensitization and structure of a Tb³⁺/2-hydroxyquinoline conjugate in the paraoxonase 1 active site.

Dalton Trans
Smerkolj J, Bahun M, Poklar Ulrih N, Bavec A, Pavšič M, Goličnik M.   +5 more
europepmc   +1 more source

Cullin-3 and Regulatory Biomolecules Profiling in Vitiligo: Integrated Docking, Clinical, and In Silico Insights. [PDF]

Biomolecules
Abdellatif HAA, Azab M, El-Sayed EH, Halim RMMM, Milebary AJ, Alenizi DA, Fawzy MS, Abd El-Fadeal NM.   +7 more
europepmc   +1 more source

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

Advanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam, Xiaoqi Wang, Grace Chung Yan Chan, Wai Po Kong, Wai Yin Chau, Xiuqiong Fu, Kwok‐Yin Wong, Hong Lok Lung, Zhi‐Ling Yu, Wei Shen Aik   +9 more
wiley   +1 more source

Design and Evaluation of Andrographolide Analogues as SARS-CoV-2 Main Protease Inhibitors: Molecular Modeling and in vitro Studies. [PDF]

Drug Des Devel Ther
Suriya U, Intamalee P, Saeeng R, Wilasluck P, Deetanya P, Wangkanont K, Kanjanasirirat P, Wongwitayasombat C, Nutho B.   +8 more
europepmc   +1 more source

Covalent Organic Frameworks for Photocatalysis

Advanced Materials, EarlyView.
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra, Akhtar Alam, Avanti Chakraborty, Bidhan Kumbhakar, Samrat Ghosh, Pradip Pachfule, Arne Thomas   +6 more
wiley   +1 more source

Toward Predictive Models of Biased Agonists of the Mu Opioid Receptor. [PDF]

Biochemistry
Tun-Rosado FJ, Abreu-Martínez EE, Magdaleno-Rodriguez A, Martinez-Mayorga K.   +3 more
europepmc   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

Discovery of First-in-Class Inhibitors Targeting a Pathogen-Associated Aminoglycoside-Resistance 16S rRNA Methyltransferase. [PDF]

ACS Infect Dis
Dey D, Deprez BE, Zelinskaya N, Castro JM, Wuest WM, Conn GL.   +5 more
europepmc   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

Combining MicroED and native mass spectrometry for structural discovery of enzyme-small molecule complexes. [PDF]

Proc Natl Acad Sci U S A
Vlahakis NW, Flowers CW, Liu M, Agdanowski MP, Johnson S, Summers JA, Jacobs LMC, Keyser C, Russell P, Rose SL, Orlans J, Adhami N, Chen Y, Sawaya MR, Basu S, de Sanctis D, Chen Y, Wakatsuki S, Nelson HM, Loo JA, Tang Y, Rodriguez JA.   +21 more
europepmc   +1 more source