Results 211 to 220 of about 1,373,014 (370)

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

Advanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim, Sung Sik Hur, Jae Hong Park, Myung Jin Ban, Jin‐Young Kim, Joo Hyun Kim, Ji Hyae Choo, Hae‐Won Kim, Ju Hun Lee, Man Ryul Lee, Yongsung Hwang   +10 more
wiley   +1 more source

Transition Metal Catalysis Drives Innovative Activity-Based Sensing Systems. [PDF]

Trends Chem
Giger AI, Kaur R, Dacon NJ, Michel BW.
europepmc   +1 more source

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

Advanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li, Adriana‐Monica Radu, Azadeh Rezaei, Joel Turner, Kaveh Shakib, Akiko Obata, Toshihiro Kasuga, Gavin Jell   +7 more
wiley   +1 more source

Structure-function studies of Vibrio cholerae quorum-sensing receptor CqsR signal recognition. [PDF]

PLoS Pathog
Guarnaccia AM, Steenhaut AD, Olenic SD, Na J, Perez LJ, Ng WL, Neiditch MB.   +6 more
europepmc   +1 more source

Bone‐Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A tunable methacrylated decellularized bone matrix hydrogel (dECM‐MA) is developed to support 3D culture of human osteoblasts. The hydrogel preserves bone‐specific ECM cues and allows precise control over mechanical properties. This system provides a customizable platform for studying osteogenic differentiation and modeling bone tissue environments for
Minne Dekker, Luke Hipwood, Akhilandeshwari Ravichandran, Dietmar W. Hutmacher, Christoph Meinert, Jacqui McGovern   +5 more
wiley   +1 more source

Simulating Metal Complex Formation and Ligand Exchange: Unraveling the Interplay between Entropy, Kinetics, and Mechanisms on the Chelate Effect. [PDF]

J Chem Theory Comput
Sagresti L, Benedetti L, Merz KM, Brancato G.   +3 more
europepmc   +1 more source

Diversity and conservation of interactions for binding heme in b-type heme proteins [PDF]

, 2007
Marles-Wright, Jon, Paoli, Max, Schneider, Sabine, Sharp, Katherine H   +3 more
core   +1 more source

Graphene‐Enhanced Plasmonic Interfaces: A General Strategy for Highly Sensitive Detection of Biomolecular Interactions

Advanced Healthcare Materials, EarlyView.
Monolayer graphene coating significantly enhances the sensing performance of conventional SPR biosensors. Its impact is evaluated using biologically relevant models, including antibody‐virus and peptide‐cell interactions. Graphene‐enhanced SPR enabled specific virus detection via antibodies and effective cell type discrimination using synthetic ...
Ahmar Hasnain, Heiko Heilmann, Nghi Luong Phuong Le, Klaus‐Ingmar Pfrepper, Andreas Wruck, Peter Groß, Bernd Bufe, Alexey Tarasov   +7 more
wiley   +1 more source

Exploring Dolichos lablab compounds as potential inhibitors for fusion (F) protein of human metapneumovirus (HMPV): A systematic computational approach. [PDF]

PLoS One
Hossain MM, Apu MJH, Aziz MFBA, Tanjil MTR, Das LC, Kar A, Evamoni FZ, Morshed MM.   +7 more
europepmc   +1 more source

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior

Advanced Healthcare Materials, EarlyView.
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley   +1 more source