Results 211 to 220 of about 379,006 (309)

The Cu\u3csub\u3eA\u3c/sub\u3e Center of a Soluble Domain from \u3cem\u3eThermus\u3c/em\u3e cytochrome ba\u3csub\u3e3\u3c/sub\u3e. An NMR Investigation of the Paramagnetic Protein. A Proton NMR Study of the Paramagnetic Active Site of the Cu\u3csub\u3eA\u3c/sub\u3e Variant of Amicyanin [PDF]

, 1998
Holz, Richard C.
core   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Native metabolomics identifies pteridines as CutA ligands and modulators of copper binding. [PDF]

Proc Natl Acad Sci U S A
Wagner BC, Steuer-Lodd K, Geibel C, Stadelmann A, Rapp J, Link H, Schramm T, Boodaghian N, Hsiao A, Nussbaum E, Grenzendorfer HP, Albrecht R, Hartmann MD, Forchhammer K, Selim KA, Hughes CC, Petras D.   +16 more
europepmc   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Special Issue "Biomolecular Structure, Function and Interactions". [PDF]

Int J Mol Sci
Crnolatac I.
europepmc   +1 more source

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

Advanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim, Seokheon Hong, Jae Hwi Lee, Jongmin Lee, Jae Jun Kang, Jiseon Bae, Jino Kim, Dong‐Hwee Kim, Jin Yoo, Mi Sun Cha, Su Hee Kim, Youngmee Jung   +11 more
wiley   +1 more source

In-silico assessment of phytochemical derivatives generated using CHEESE webserver for advancement of druggable candidate in pancreatic cancer therapy. [PDF]

In Silico Pharmacol
Olowosoke CB, Ishabiyi FO, Bouribab A, Munir A, Awoyemi B, Nsofo WN, Christabel AC, Joy JO, Chtita S, Omoboyede V, Chukwuemeka PO.   +10 more
europepmc   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Optimizing Stability in Dynamic Small-Molecule Binding Proteins. [PDF]

J Am Chem Soc
Scherer M, Kriegel M, Höcker B, Fleishman SJ.   +3 more
europepmc   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source