Results 221 to 230 of about 363,417 (316)

Mechanochemistry for Metal–Organic Frameworks and Covalent–Organic Frameworks (MOFs, COFs): Methods, Materials, and Mechanisms

Advanced Materials, EarlyView.
An overview is provided of the mechanochemistry of metal‐organic frameworks (MOFs) and covalent‐organic frameworks (COFs), highlighting opportunities and strategies for discovery, synthesis and reactivity studies of these materials. Mechanistic studies and comparisons to the mechanochemistry of organic solids are outlined, showcasing how advances in ...
Joseph M. Marrett, Farshid Effaty, Xavier Ottenwaelder, Tomislav Friščić   +3 more
wiley   +1 more source

Structure-based identification of bioactive compounds as trace amine-associated receptor 1 agonists for the therapeutic management of major depressive disorder. [PDF]

PLoS One
Elasbali AM, Ali AS, Adnan M, Mohammad T, Shamsi A, Hassan MI.   +5 more
europepmc   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

Unraveling potential EGFR kinase inhibitors: Computational screening, molecular dynamics insights, and MMPBSA analysis for targeted cancer therapy development. [PDF]

PLoS One
Khan MN, Farooq U, Khushal A, Wani TA, Zargar S, Khan S.   +5 more
europepmc   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Design of Potent Mannose-6-Phosphate Derivatives as Ligands for CI-M6P/IGF2R Using Fluorescence Polarization Assay. [PDF]

Chemistry
Mrázková L, Hladoníková K, Toncarová B, Fischer M, Zýka J, Kozák J, Kráľ M, Kožíšek M, Jiráček J, Kaminský J, Parkan K, Žáková L.   +11 more
europepmc   +1 more source

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

Advanced Materials, EarlyView.
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang, Jordi Guillem‐Marti, Saurav Kumar, David S. Lee, Daniel Cabrerizo‐Aguado, Rachel Werther, Kevin Alexander Estrada Alamo, Yan Ting Zhao, Adam Nguyen, Irina Kopyeva, Buwei Huang, Jing Li, Yuxin Hao, Xinting Li, Aritza Brizuela‐Velasco, Analisa Murray, Stacey Gerben, Anindya Roy, Cole A. DeForest, Timothy Springer, Hannele Ruohola‐Baker, Jonathan A. Cooper, Melody G. Campbell, Jose Maria Manero, Maria‐Pau Ginebra, David Baker   +25 more
wiley   +1 more source

Relative Binding Free Energy Estimation of Congeneric Ligands and Macromolecular Mutants with the Alchemical Transfer Method with Coordinate Swapping. [PDF]

J Chem Inf Model
Gallicchio E.
europepmc   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Structural changes of tubulin by interacting with Δ⁹-tetrahydrocannabinol: in-vitro and theoretical studies. [PDF]

BMC Neurosci
Mohammadkhani M, Jarah M, Gholami D, Riazi G, Rezazadeh H.   +4 more
europepmc   +1 more source