Results 261 to 270 of about 363,417 (316)

Identification of novel HER2 ınhibitors: potential therapeutics for breast cancer. [PDF]

Discov Oncol
Yalaza C, Antmen SE, Acuner SE, Oz H, Bulut E, Canacankatan N.   +5 more
europepmc   +1 more source

In Silico identification and modelling of FDA-approved drugs targeting T-type calcium channels. [PDF]

PLoS One
Fong P, Garcia SR, Stefan MI, Sterratt DC.   +3 more
europepmc   +1 more source

Evaluating the inhibitory efficacy of Oxalis phytocompounds on monoamine oxidase B: An integrated approach targeting age related neurodegenerative diseases through molecular docking and dynamics simulations. [PDF]

PLoS One
Shrestha RLS, M C S, Tamang A, Poudel M, Parajuli N, Shrestha A, Shrestha T, Bharati S, Maharjan B, Marasini BP, Adhikari Subin J.   +10 more
europepmc   +1 more source

Accurate Prediction of Drug Activity by Computational Methods: Importance of Thermal Capacity. [PDF]

Molecules
Palese LL.
europepmc   +1 more source

Efficient Crystallization of Apo Sirt2 for Small-Molecule Soaking and Structural Analysis of Ligand Interactions. [PDF]

J Med Chem
Friedrich F, Schiedel M, Swyter S, Zhang L, Sippl W, Schutkowski M, Einsle O, Jung M.   +7 more
europepmc   +1 more source

Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand

Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand
openaire  

Dinitrosyl iron complexes with thiolate ligands: Physico-chemistry, biochemistry and physiology

Nitric Oxide, 2009
Some present-day concepts on the origin and functional activities of dinitrosyl iron complexes (DNIC) with thiolate ligands are considered. Nitric oxide (NO) including to DNIC increases its stability and ensures effective targeting of NO to organs and tissues.
А. Ф. Ванин
openalex   +4 more sources

Histamine Receptors: Specific Ligands, Receptor Biochemistry, and Signal Transduction

, 2002
During the past few years, there has been a tremendous increase in our understanding of the histamine receptors. Important progress has been made in the development of H1-receptor agonists and the rationalization of H1-receptor-ligand interaction. The recent observation of constitutive H1- and H2-receptor activity has led to a reclassification of H1 ...
Remko A. Bakker, H. Timmerman, Rob Leurs
openalex   +5 more sources

Experimental Design and Polyelectrolyte Effects on Ligand Binding to Nucleic Acids. An Undergraduate Biochemistry Lab

Journal of Chemical Education, 2002
We have developed an experiment that utilizes the salt dependence of spermine binding to DNA as a means to introduce experimental design concepts and polyelectrolyte effects in the undergraduate biochemistry lab. The experiment is easily completed in two, three-hour lab periods.
Matthew A. Fisher, Danielle Johnston, Daniel A. Ritt   +2 more
openalex   +3 more sources

Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand

Progress in Lipid Research, 2006
2-Arachidonoylglycerol (2-AG) is a unique molecular species of monoacylglycerol isolated in 1995 from rat brain and canine gut as an endogenous ligand for the cannabinoid receptors. 2-AG is rapidly formed from arachidonic acid-containing phospholipids through increased phospholipid metabolism, such as enhanced inositol phospholipid turnover, in various
T. SUGIURA, S KISHIMOTO, Satoshi Oka, Maiko Gokoh   +3 more
openalex   +3 more sources