Results 111 to 120 of about 1,596,891 (346)

Control of Interpenetration and Gas‐Sorption Properties of Metal–Organic Frameworks by a Simple Change in Ligand Design [PDF]

, 2012
T.K. Prasad, Myunghyun Paik Suh
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Systematics of BX₃ and BX₂⁺ Complexes (X = F, Cl, Br, I) with Neutral Diphosphine and Diarsine Ligands [PDF]

, 2016
Jennifer Burt, J.W. Emsley, William Levason, Gillian Reid, Iain S. Tinkler   +4 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Chelating Properties of N₆O-Donors Toward Cu(II) Ions: Speciation in Aqueous Environments and Catalytic Activity of the Dinuclear Complexes

Molecules
This study focuses on the use of three isostructural N6O donor ligands, specifically known to form complexes with copper ions, to chelate Cu(II) from aqueous solutions.
Andrea Cendron, Martina Chianese, Kamil Zarzycki, Paolo Ruzza, Claudia Honisch, Justyna Brasuń, Mauro Carraro   +6 more
doaj   +1 more source

Ligands for FKBP12 Increase Ca2+ Influx and Protein Synthesis to Improve Skeletal Muscle Function [PDF]

, 2014
Chang Seok Lee, Dimitra K. Georgiou, Adán Dagnino-Acosta, Jianjun Xu, Iskander I. Ismailov, Mark Knoblauch, Tanner O. Monroe, RuiRui Ji, Amy D. Hanna, Aditya Joshi, Cheng Long, Joshua M. Oakes, Ted Tran, Benjamin T. Corona, Sabina Lorca, Christopher P. Ingalls, Vihang A. Narkar, Johanna T. Lanner, J. Henri Bayle, William J. Durham, Susan L. Hamilton   +20 more
openalex   +1 more source

Decision letter for "EGFR ligands synergistically increase IL‐17A‐induced expression of psoriasis signature genes in human keratinocytes via IκBζ and Bcl3"

, 2021

openalex   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Effective adhesion strength of specifically bound vesicles

, 2005
A theoretical approach has been undertaken in order to model the thermodynamic equilibrium of a vesicle adhering to a flat substrate. The vesicle is treated in a canonical description with a fixed number of sites.
Ana-Sunčana Smith, L. D. Landau, P. Bongrand, R. Bruinsma, Udo Seifert   +4 more
core   +1 more source

Recent Advance of Amino-acids and Their Derivatives as Chiral Ligands in Asymmetric Transfer Hydrogenation of Ketones [PDF]

, 2012
Xiaona Li, Pengliang Zhang, Kai Duan, Jiaxi Wang   +3 more
openalex   +1 more source