Results 11 to 20 of about 905,008 (316)
A dense and diverse array of glycans on glycoproteins and glycolipids decorate all cell surfaces. In vertebrates, many of these carry sialic acid, in a variety of linkages and glycan contexts, as their outermost sugar moiety. Among their functions, glycans engage complementary glycan binding proteins (lectins) to regulate cell physiology.
Anabel Gonzalez-Gil, Ronald L. Schnaar
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Polymer or macrocycle? : cobalt complexes of ditopic 2,2':6',2"-terpyridine ligands with flexible spacers [PDF]
The reaction of transition metal ions with ditopic ligands containing two 2,2':6',2"-terpyridine units linked by flexible spacers can give metallosupramolecular polymers, discrete metallomacrocycles or mixtures of the two.
Harris, Emily Kate
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Aryl Hydrocarbon Receptor as an Anticancer Target: An Overview of Ten Years Odyssey
Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor belonging to the basic helix–loop–helix (bHLH)/per-Arnt-sim (PAS) superfamily, is traditionally known to mediate xenobiotic metabolism.
Hamza Hanieh +4 more
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Novel chalcone-based fluorescent human histamine H 3 receptor ligands as pharmacological tools [PDF]
Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif.
Miriam Tomasch +7 more
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Advances on Mrgprs itch receptors and their ligands
Although histamine is an important physiologically active substance in pruritus,antihistamine drugs can only relieve a small proportion of symptoms in chronic pruritus.
Jing HU, Zhijian CAO
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Investigating silver coordination to mixed chalcogen ligands [PDF]
The work in this project was supported by the Engineering and Physical Sciences Research Council (EPSRC).Six silver(I) coordination complexes have been prepared and structurally characterised. Mixed chalcogen-donor acenaphthene ligands L1–L3 [Acenap(EPh)(
Slawin, Alexandra Martha Zoya +9 more
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Metal–ligand cooperation at tethered π-ligands
Recent advances in the use of tethered π-coordinating ligands for metal–ligand cooperation.
Dide G. A. Verhoeven, Marc-Etienne Moret
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New bisphosphine ligands for asymmetric catalysis [PDF]
The success of homogeneous asymmetric catalysis has been attributed to the structure and stereochemistry of the coordinated ligand(s). The most effective ligands are C2-symmetrical bisphosphines containing either a rigid chiral backbone linking two PPh2 ...
Carey, Joseph Vincent +1 more
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Aptamer-Based Technologies in Foodborne Pathogen Detection
Aptamers are single stranded DNA or RNA ligands, which can be selected by a method called systematic evolution of ligands by exponential enrichment (SELEX); and they can specifically recognize and bind to their targets.
Jun Teng +7 more
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CAT-Site: Predicting Protein Binding Sites Using a Convolutional Neural Network
Identifying binding sites on the protein surface is an important part of computer-assisted drug design processes. Reliable prediction of binding sites not only assists with docking algorithms, but it can also explain the possible side-effects of a ...
Žan Hafner Petrovski +2 more
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