Results 21 to 30 of about 1,019,350 (256)

Human Cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against NK cell cytotoxicity. [PDF]

, 2003
The activating receptor, NKG2D, is expressed on a variety of immune effector cells and recognizes divergent families of major histocompatibility complex (MHC) class I-related ligands, including the MIC and ULBP proteins.
Sutherland, CL, Johnson, DC, N. Jan Chalupny, Chalupny, NJ, Claire Dunn, Sivakumar, PV, P.V. Sivakumar, Dunn, C, Dosch, S, David Cosman, David C. Johnson, Cosman, D, Stephanie Dosch, Claire L. Sutherland   +13 more
core   +1 more source

A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy

Frontiers in Molecular Neuroscience, 2018
C-to-U RNA editing of glycine receptors (GlyR) can play an important role in disease progression of temporal lobe epilepsy (TLE) as it may contribute in a neuron type-specific way to neuropsychiatric symptoms of the disease.
Svenja Kankowski, Benjamin Förstera, Aline Winkelmann, Pina Knauff, Erich E. Wanker, Xintian A. You, Marcus Semtner, Florian Hetsch, Jochen C. Meier   +8 more
doaj   +1 more source

Mercury(II) Complexes of Anionic N-Heterocyclic Carbene Ligands: Steric Effects of the Backbone Substituent

Molecules, 2020
Mercury(II) complexes (Me-maloNHCDipp)HgCl (1b), (t-Bu-maloNHCDipp)HgCl (2b) and (t-Bu-maloNHCDipp)HgMe (2c) supported by anionic N-heterocyclic carbenes have been obtained in good yields from the reaction of the potassium salt of N-heterocyclic carbene ...
Chandrakanta Dash, Animesh Das, H. V. Rasika Dias   +2 more
doaj   +1 more source

Bovine Holo-Beta-Lactoglobulin Cross-Protects Against Pollen Allergies in an Innate Manner in BALB/c Mice: Potential Model for the Farm Effect

Frontiers in Immunology, 2021
The lipocalin beta-lactoglobulin (BLG) is a major protein compound in cow’s milk, and we detected it in cattle stable dust. BLG may be a novel player in the farm protective effect against atopic sensitization and hayfever.
Sheriene Moussa Afify, Sheriene Moussa Afify, Sheriene Moussa Afify, Isabella Pali-Schöll, Isabella Pali-Schöll, Karin Hufnagl, Gerlinde Hofstetter, Maha Abdel-Rafea El-Bassuoni, Franziska Roth-Walter, Franziska Roth-Walter, Erika Jensen-Jarolim, Erika Jensen-Jarolim, Erika Jensen-Jarolim   +12 more
doaj   +1 more source

Crystallographic study of PET radiotracers in clinical evaluation for early diagnosis of Alzheimers

Acta Crystallographica Section E, 2014
The title compound, C24H25NO3·2CH3OH, which crystallized as a methanol disolvate, has applications as a PET radiotracer in the early diagnosis of Alzheimer's disease.
Angela Altomare, Elena Capparelli, Antonio Carrieri, Nicola A. Colabufo, Anna Moliterni, Rosanna Rizzi, Dritan Siliqi   +6 more
doaj   +1 more source

Inhibitory Immune Checkpoint Receptors and Ligands as Prognostic Biomarkers in COVID-19 Patients

Frontiers in Immunology, 2022
Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2. During T-cell activation, the immune system uses different checkpoint pathways to maintain co-inhibitory and co-stimulatory signals.
Mohammad A. Al-Mterin, Alhasan Alsalman, Eyad Elkord, Eyad Elkord   +3 more
doaj   +1 more source

Molecular mechanisms and kinetics between DNA and DNA binding ligands [PDF]

, 2005
Sischka A, Tönsing K, Eckel R, et al. Molecular mechanisms and kinetics between DNA and DNA binding ligands. Biophysical Journal. 2005;88(1):404-411.Mechanical properties of single double-stranded DNA (dsDNA) in the presence of different binding ligands ...
Wilking, Sven David, Ros, Robert, Sischka, Andy, Eckel, Rainer, Tönsing, Katja, Sewald, Norbert ; https://orcid.org/, Anselmetti, Dario ; https://orcid.org/   +6 more
core   +1 more source

Synthesis and Characterization of two Closed Side Oxadiazole ligands with their Related Complexes Cu( II ) and Pd(II) [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2012
The two oxadiazole new ligands of bis oxadiazol derivatives, have been synthesized by the reaction of (L1)and , oxadiazol-2yl] methane (L2.) with adibic acid in presence of ethnolic solution of potassium hydroxide.
Hikmat A. mohamad
doaj   +1 more source

Spotlight on Nociceptin/Orphanin FQ Receptor in the Treatment of Pain

Molecules, 2022
In our society today, pain has become a main source of strain on most individuals. It is crucial to develop novel treatments against pain while focusing on decreasing their adverse effects. Throughout the extent of development for new pain therapies, the
Amal El Daibani, Tao Che
doaj   +1 more source

Some geometric aspects of polyvalent systems modeling

Lietuvos Matematikos Rinkinys, 2012
In this paper we consider the interaction of ligands and receptors on the plane and in the space.
Irus Grinis, Feliksas Ivanauskas, Gediminas Stepanauskas   +2 more
doaj   +1 more source