Results 21 to 30 of about 901,811 (316)

Trace metals in the open oceans: speciation modelling based on humic type ligands [PDF]

open access: yes, 2011
The speciation of trace metals in the oceans is typically explained by invoking the concept of metal binding to specific organic ligands, but a lack of detailed knowledge about the ligands has impeded the formulation of comprehensive models to predict ...
Stockdale, Anthony   +7 more
core   +1 more source

A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy

open access: yesFrontiers in Molecular Neuroscience, 2018
C-to-U RNA editing of glycine receptors (GlyR) can play an important role in disease progression of temporal lobe epilepsy (TLE) as it may contribute in a neuron type-specific way to neuropsychiatric symptoms of the disease.
Svenja Kankowski   +8 more
doaj   +1 more source

Mercury(II) Complexes of Anionic N-Heterocyclic Carbene Ligands: Steric Effects of the Backbone Substituent

open access: yesMolecules, 2020
Mercury(II) complexes (Me-maloNHCDipp)HgCl (1b), (t-Bu-maloNHCDipp)HgCl (2b) and (t-Bu-maloNHCDipp)HgMe (2c) supported by anionic N-heterocyclic carbenes have been obtained in good yields from the reaction of the potassium salt of N-heterocyclic carbene ...
Chandrakanta Dash   +2 more
doaj   +1 more source

Bovine Holo-Beta-Lactoglobulin Cross-Protects Against Pollen Allergies in an Innate Manner in BALB/c Mice: Potential Model for the Farm Effect

open access: yesFrontiers in Immunology, 2021
The lipocalin beta-lactoglobulin (BLG) is a major protein compound in cow’s milk, and we detected it in cattle stable dust. BLG may be a novel player in the farm protective effect against atopic sensitization and hayfever.
Sheriene Moussa Afify   +12 more
doaj   +1 more source

Crystallographic study of PET radiotracers in clinical evaluation for early diagnosis of Alzheimers

open access: yesActa Crystallographica Section E, 2014
The title compound, C24H25NO3·2CH3OH, which crystallized as a methanol disolvate, has applications as a PET radiotracer in the early diagnosis of Alzheimer's disease.
Angela Altomare   +6 more
doaj   +1 more source

Inhibitory Immune Checkpoint Receptors and Ligands as Prognostic Biomarkers in COVID-19 Patients

open access: yesFrontiers in Immunology, 2022
Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2. During T-cell activation, the immune system uses different checkpoint pathways to maintain co-inhibitory and co-stimulatory signals.
Mohammad A. Al-Mterin   +3 more
doaj   +1 more source

Control of Notch-ligand endocytosis by ligand-receptor interaction [PDF]

open access: yesDevelopment, 2010
In Notch signaling, cell-bound ligands activate Notch receptors on juxtaposed cells, but the relationship between ligand endocytosis, ubiquitylation and ligand-receptor interaction remains poorly understood. To study the specific role of ligand-receptor interaction, we identified a missense mutant of the Notch ligand Jagged1 (Nodder, Ndr) that failed ...
Hansson, E. M.   +10 more
openaire   +3 more sources

Synthesis and Characterization of two Closed Side Oxadiazole ligands with their Related Complexes Cu( II ) and Pd(II) [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
The two oxadiazole new ligands of bis oxadiazol derivatives, have been synthesized by the reaction of (L1)and , oxadiazol-2yl] methane (L2.) with adibic acid in presence of ethnolic solution of potassium hydroxide.
Hikmat A. mohamad
doaj   +1 more source

Spotlight on Nociceptin/Orphanin FQ Receptor in the Treatment of Pain

open access: yesMolecules, 2022
In our society today, pain has become a main source of strain on most individuals. It is crucial to develop novel treatments against pain while focusing on decreasing their adverse effects. Throughout the extent of development for new pain therapies, the
Amal El Daibani, Tao Che
doaj   +1 more source

Some geometric aspects of polyvalent systems modeling

open access: yesLietuvos Matematikos Rinkinys, 2012
In this paper we consider the interaction of ligands and receptors on the plane and in the space.
Irus Grinis   +2 more
doaj   +1 more source

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