In Vitro Selection of a New Lanthanide-Dependent DNAzyme for Ratiometric Sensing Lanthanides [PDF]
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Analytical Chemistry, copyright © American Chemical Society after peer review and technical editing by publisher. To access the final edited and published
Huang, Po-Jung Jimmy+2 more
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Abstract Viral infections are major contributors to crop yield loss and represent a significant threat to sustainable agriculture. Plants respond to virus attacks by activating sophisticated signalling cascades that initiate multiple defence mechanisms.
Kritika Shukla+4 more
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Design and synthesis of probes for detection of protein-protein interaction and RNA localization [PDF]
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005.Includes bibliographical references.The use of the ketone biotin - benzophenone-biotin hydrazide system for detecting the formation of cyan fluorescent protein and NF-kappaB ...
Ryan, Jeremy Adam
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Continual reproduction of self-assembling oligotriazole peptide nanomaterials. [PDF]
Autocatalytic chemical reactions, whereby a molecule is able to catalyze its own formation from a set of precursors, mimic nature's ability to generate identical copies of relevant biomolecules, and are thought to have been crucial for the origin of life.
Brea, Roberto J, Devaraj, Neal K
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The 2'-5' RNA Ligase of Escherichia coli: Purification, Cloning, and Genomic Disruption [PDF]
An RNA ligase previously detected in extracts of Escherichia coli is capable of joining Saccharomyces cerevisiae tRNA splicing intermediates in the absence of ATP to form a 2-5 phosphodiester linkage (Greer, C., Javor, B., and Abelson, J. (1983) Cell 33,
Abelson, John N., Arn, Eric A.
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Capturing the ‘ome’ : the expanding molecular toolbox for RNA and DNA library construction [PDF]
All sequencing experiments and most functional genomics screens rely on the generation of libraries to comprehensively capture pools of targeted sequences.
Boone, Morgane+2 more
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Aptasensors and Advancement in Molecular Recognition Technology
This review summarizes how aptamers (chemical antibodies)‐based biosensors are developed and applied to biological and biomedical research as well as clinical diagnostics. How a nucleic acid‐based biosensor platform is poised to become the next generation of sensitive and cost‐effective technology will be showcased, shaping the future of biosensing ...
Rajindra Napit+10 more
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The Fibroblast Growth Factor-binding Protein (FGF-BP) and the Human Epidermal Growth Factor Receptor-2 (HER-2): functional studies on two gene products relevant in Ovarian cancer [PDF]
Ovarialkarzinome gehören zu den weitverbreitetsten und lebensgefährlichsten gynäkologischen Tumoren mit bislang begrenzten Behandlungsmöglichkeiten.
Abuharbeid Shaker+1 more
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Elucidating Evolutionary Mechanisms and Variants of the Hammerhead Ribozyme Using In Vitro Selection
We generated single‐, double‐, and triple‐mutation libraries to explore the sequence requirements and evolution of a full‐length hammerhead ribozyme. We identified many hammerhead variants, some of which possess mutations at previously considered essential nucleotides. We also present a novel methodological approach for evaluating the sequence‐function
Jake Brill, Connor Nurmi, Yingfu Li
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The Implementation and Efficacy of Scientific Literature within an Introductory Biology Lecture Course:A Study in Pedagogy, Curricula, and Standards as They Apply to Post-Secondary Science Education [PDF]
The current study involved students enrolled in the Fall 2007 Biosc 0150 and Spring 2008 Biosc 0160 lecture sections of a single Faculty member. Most students were incoming freshmen, and their prior exposure to the natural sciences varied.
Tomaszewski, Shaun Allen
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