Results 201 to 210 of about 120,350 (347)

Emerging roles for E3 ubiquitin ligases in neural development and disease. [PDF]

Front Cell Dev Biol
Hale M, Bashaw GJ.
europepmc   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu, Shaobo Kang, Na Lin, Wenqi Zhang, Shiwen Wang, Yuqing Ren, Xiaofan Ding, Jianxiu Yu, Ruiyu Xie   +8 more
wiley   +1 more source

Crystal structure of ATP-dependent DNA ligase from Rhizobium phage vB_RleM_P10VF. [PDF]

Acta Crystallogr F Struct Biol Commun
Rothweiler U, Leiros HKS, Williamson A.
europepmc   +1 more source

Reconstruction of tRNA^Phe molecules from the fragments by linkage with T‐4 RNA ligase in double‐stranded regions [PDF]

, 1984
A.S. Boutorin, Stanislav Vassilenko, Michail M. Baklanov, Yu. S. Nechaev   +3 more
openalex   +1 more source

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

Advanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen, Li Gong, Wei Yang, Jiaqi Luo, Zhen Jin, Youzhi Tang   +5 more
wiley   +1 more source

Manipulation of targeted protein degradation in plant biology. [PDF]

Biochem Soc Trans
Rojas-Pierce M, Bednarek SY.
europepmc   +1 more source

Regulation of benzoate-CoA ligase inRhodopseudomonas palustris [PDF]

, 1991
Min-Kyung Kim, Caroline S. Harwood
openalex   +1 more source

Trimerization of 1,2‐Diaminocyclohexane Catalyzed by a Metal–Organic Cage Tandem Catalyst with Dual Biomimetic Active Sites

Advanced Science, EarlyView.
Dual biomimetic active sites, i.e., mononuclear {ZnII(L)(H2O)} and dinuclear {L2ZnII(CHO2)(OH)ZnIIL2}, have been successfully intergrated into a metal–organic cage, Zn20‐MOC. These two different active sites in Zn20‐MOC catalyze different steps of cascade trimerization of 1,2‐diaminocyclohexane. The mononuclear {ZnII(L)(H2O)} site catalyzes the initial
Xiao‐Jun Chai, Zhu Zhuo, Zi‐Ang Nan, Shiqiang Mu, Zhong‐Yu Peng, Ting Chen, Wei Wang, Li‐Feng Lin, Xi Meng, Mao‐Chun Hong, You‐Gui Huang   +10 more
wiley   +1 more source

Control of Snail1 protein stability by post-translational modifications: the basis for a complex regulation of Snail1 function. [PDF]

Int J Biol Sci
García de Herreros A.
europepmc   +1 more source

Single crystal x-ray study of leucyl-tRNA-aminoacyl-ligase using an image intensifier-aided detection system

, 1974
James R. Milch
openalex   +1 more source