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Current Protocols in Molecular Biology, 1991
AbstractT4 RNA ligase, the product of the phage gene 63, is purified from phage‐infected cells. It catalyzes the ATP‐dependent covalent joining of single‐stranded 5'‐phosphoryl termini of DNA or RNA to single‐stranded 3'‐hydroxyl termini of DNA or RNA. This unit describes specific reaction conditions as well as applications such as radioactive labeling
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AbstractT4 RNA ligase, the product of the phage gene 63, is purified from phage‐infected cells. It catalyzes the ATP‐dependent covalent joining of single‐stranded 5'‐phosphoryl termini of DNA or RNA to single‐stranded 3'‐hydroxyl termini of DNA or RNA. This unit describes specific reaction conditions as well as applications such as radioactive labeling
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2010
Ligase IV (LIG4) syndrome belongs to the group of hereditary disorders associated with impaired DNA damage response mechanisms. Clinically and morphologically, patients affected with this syndrome are characterized by microcephaly, unusual facial features, growth retardation, developmental delay, skin anomalies and are typically pancytopenic.
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Ligase IV (LIG4) syndrome belongs to the group of hereditary disorders associated with impaired DNA damage response mechanisms. Clinically and morphologically, patients affected with this syndrome are characterized by microcephaly, unusual facial features, growth retardation, developmental delay, skin anomalies and are typically pancytopenic.
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Discovery, characterization and engineering of ligases for amide synthesis
Nature, 2021Jason Micklefield +2 more
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The role of E3 ubiquitin ligases in the development and progression of glioblastoma
Cell Death and Differentiation, 2021Vincenzo D'Angiolella +2 more
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E3-ubiquitin ligases and recent progress in osteoimmunology
Frontiers in Immunology, 2023Yoshinori Matsumoto +2 more
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The Role of SUMO E3 Ligases in Signaling Pathway of Cancer Cells
International Journal of Molecular Sciences, 2022Huijian Wu, Shujing Li, Yixin Du
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