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Function and Regulation of Cullin–RING Ubiquitin Ligases

Nature Reviews Molecular Cell Biology, 2005
Cullin–RING complexes comprise the largest known class of ubiquitin ligases. Owing to the great diversity of their substrate-receptor subunits, it is possible that there are hundreds of distinct cullin–RING ubiquitin ligases in eukaryotic cells, which ...
Raymond J. Deshaies, Matthew D Petroski
exaly   +2 more sources

Dual BACH1 Regulation by Complementary SCF-Type E3 Ligases [PDF]

Cell
Broad-complex, tramtrack, and bric-à-brac domain (BTB) and CNC homolog 1 (BACH1) is a key regulator of the cellular oxidative stress response and an oncogene that undergoes tight post-translational control by two distinct F-box ubiquitin ligases ...
Benedikt Goretzki, César Fernández
exaly   +2 more sources

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C-Degron Mimicry Confers E3 Ligase Selectivity

Nature Reviews Molecular Cell Biology, 2023
Lisa Heinke
exaly  

Systemwide Disassembly and Assembly of SCF Ubiquitin Ligase Complexes

Cell, 2023
Brenda Schulman, Kheewoong Baek, Daniel C Scott   +2 more
exaly  

E3 Ligases Team Up

Nature Reviews Molecular Cell Biology, 2011
Katharine Wrighton
exaly