Labelling of l-Isoleucine tRNA Ligase from Escherichia coli with l-Isoleucyl-bromomethyl Ketone [PDF]
, 1976 Petrie M. Rainey +2 more
openalex +1 more source
Repair of Alkylated Bacteriophage T4 Deoxyribonucleic Acid by a Mechanism Involving Polynucleotide Ligase [PDF]
, 1971 Marian W. Baldy +2 more
openalex +1 more source
MARCH family E3 ubiquitin ligases selectively target and degrade cadherin family proteins.
PLoS ONECadherin family proteins play a central role in epithelial and endothelial cell-cell adhesion. The dynamic regulation of cell adhesion is achieved in part through endocytic membrane trafficking pathways that modulate cadherin cell surface levels.
Tadahiko Seo +6 more
doaj +1 more source
The Localization of DNA Ligase in the Chromatin of Animal Cells [PDF]
, 1973 Ajub I. Gaziev, Alexander M. Kuzin
openalex +1 more source
SUPPRESSION OF T4D LIGASE MUTATIONS BY rIIA AND rIIB MUTATIONS
, 1969 Hillard Berger, Andrzej W. Kozinski
openalex +1 more source
On an RNA-membrane protogenome [PDF]
arXivSelected ribonucleotide sequences bind well to zwitterionic phospholipid bilayer membranes, though randomized RNAs do not. There are no evident repeated sequences in selected membrane binding RNAs. This implies small and varied motifs responsible for membrane affinity. Such subsequences have been partially defined. Bound RNAs require divalents like Mg2+
arxiv
Role for deoxyribonucleic acid ligase in deoxyribonucleic acid polymerase i-dependent repair synthesis in toluene-treated escherichia coli [PDF]
, 1975 Daniel Billen +2 more
openalex +1 more source
Exploring the Role of Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease
PharmaceuticalsParkinson’s disease (PD) is a prevalent neurodegenerative disorder among the elderly population. The pathogenesis of PD encompasses genetic alterations, environmental factors, and age-related neurodegenerative processes.
Yiting Zhao +4 more
doaj +1 more source
SE(3)-Equivariant Ternary Complex Prediction Towards Target Protein Degradation [PDF]
arXivTargeted protein degradation (TPD) induced by small molecules has emerged as a rapidly evolving modality in drug discovery, targeting proteins traditionally considered "undruggable". Proteolysis-targeting chimeras (PROTACs) and molecular glue degraders (MGDs) are the primary small molecules that induce TPD.
arxiv