Results 71 to 80 of about 718,207 (427)
A new simple scheme for constructing recombinant vectors that does not require any restriction enzyme, ligase, or any other special enzyme treatment has been developed.
Akinori Kuzuya+3 more
doaj +1 more source
Abdominal Hysterectomy: A New Approach for Conventional Procedure [PDF]
Objective: The present comparative study helps in developing a new approach to conventional hysterectomy procedure so as to prevent intra-operative and Post-operative complications during the procedure.
DILIP KUMAR DUTTA, INDRANIL DUTTA
doaj +1 more source
The doppler-guided transanal hemorrhoidal dearterialization technique associated with mucopexy is a noninvasive surgical option used to treat hemorrhoidal disease (HD).
Carlos Mateus Rotta+4 more
doaj +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
Pif1 Helicase Lengthens Some Okazaki Fragment Flaps Necessitating Dna2 Nuclease/Helicase Action in the Two-nuclease Processing Pathway [PDF]
We have developed a system to reconstitute all of the proposed steps of Okazaki fragment processing using purified yeast proteins and model substrates.
Bambara, Robert A.+3 more
core +2 more sources
A Bioorthogonal Quadricyclane Ligation
New additions to the bioorthogonal chemistry compendium can advance biological research by enabling multiplexed analysis of biomolecules in complex systems. Here we introduce the quadricyclane ligation, a new bioorthogonal reaction between the highly strained hydrocarbon quadricyclane and Ni bis(dithiolene) reagents.
Carolyn R. Bertozzi, Ellen M. Sletten
openaire +3 more sources
Deep cervical lymph node ligation aggravates AD‐like pathology of APP/PS1 mice
The imbalance between production and clearance of amyloid‐beta (Aβ) is a key step in the onset and development of Alzheimer’s disease (AD). Therefore, reducing Aβ accumulation in the brain is a promising therapeutic strategy for AD.
Linmei Wang+5 more
semanticscholar +1 more source
Severe acute pancreatitis (SAP) is one of the most common diseases of the gastrointestinal tract, characterized by a complicated pathogenesis, multiple organ failure, and high mortality.
Yuanqi Liu+3 more
doaj +1 more source
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker+14 more
wiley +1 more source
YAMAT-seq: an efficient method for high-throughput sequencing of mature transfer RNAs. [PDF]
Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in various biological pathways and exhibit highly variable expression profiles.
Honda, Shozo+5 more
core +2 more sources