Results 41 to 50 of about 542,326 (219)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Generic dijet soft functions at two-loop order: correlated emissions

Journal of High Energy Physics, 2019
We present a systematic algorithm for the perturbative computation of soft functions that are defined in terms of two light-like Wilson lines. Our method is based on a universal parametrisation of the phase-space integrals, which we use to isolate the ...
Guido Bell, Rudi Rahn, Jim Talbert
doaj   +1 more source

Towards the experimental observation of turbulent regimes and the associated energy cascades with paraxial fluids of light

New Journal of Physics, 2022
The propagation of light in nonlinear optical media has been widely used as a tabletop platform for emulating quantum-like phenomena due to their similar theoretical description to quantum fluids.
Tiago D Ferreira, Vicente Rocha, Duarte Silva, Ariel Guerreiro, Nuno A Silva   +4 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

The Role of Cortisol in Chronic Stress, Neurodegenerative Diseases, and Psychological Disorders

Cells, 2023
Cortisol, a critical glucocorticoid hormone produced by the adrenal glands, plays a pivotal role in various physiological processes. Its release is finely orchestrated by the suprachiasmatic nucleus, governing the circadian rhythm and activating the ...
Emilija Knezevic, Katarina Nenic, Vladislav Milanovic, Nebojsa Nick Knezevic   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Computing Transiting Exoplanet Parameters with 1D Convolutional Neural Networks

Axioms
The transit method allows the detection and characterization of planetary systems by analyzing stellar light curves. Convolutional neural networks appear to offer a viable solution for automating these analyses.
Santiago Iglesias Álvarez, Enrique Díez Alonso, María Luisa Sánchez Rodríguez, Javier Rodríguez Rodríguez, Saúl Pérez Fernández, Francisco Javier de Cos Juez   +5 more
doaj   +1 more source

Vasopressinergic Activity of the Suprachiasmatic Nucleus and mRNA Expression of Clock Genes in the Hypothalamus-Pituitary-Gonadal Axis in Female Aging

Frontiers in Endocrinology, 2021
The important involvement of the suprachiasmatic nucleus (SCN) and the activity of vasopressinergic neurons in maintaining the rhythmicity of the female reproductive system depends on the mRNA transcription-translation feedback loops.
Angela Cristina Nicola, Larissa Brazoloto Ferreira, Milene Mantovani Mata, Tatiane Vilhena-Franco, Cristiane Mota Leite, Andressa Busetti Martins, José Antunes-Rodrigues, Maristela Oliveira Poletini, Rita Cássia Menegati Dornelles, Rita Cássia Menegati Dornelles   +9 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Monochromatic green light stimulation during incubation shortened the hatching time via pineal function in White Leghorn eggs

Journal of Animal Science and Biotechnology, 2021
Background Effect of monochromatic green light illumination on embryo development has been reported in chickens. The avian pineal gland is an important photo-endocrine organ formed by a mediodorsal protrusion during embryonic development.
Panlin Wang, Yanyan Sun, Yunlei Li, Jing Fan, Yunhe Zong, Adamu Mani Isa, Lei Shi, Yuanmei Wang, Aixin Ni, Pingzhuang Ge, Linlin Jiang, Shixiong Bian, Hui Ma, Zhengdong Yuan, Xiaolin Liu, Jilan Chen   +15 more
doaj   +1 more source