Results 91 to 100 of about 13,240,817 (334)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Many-Body effects and resonances in universal quantum sticking of cold atoms to surfaces

, 1994
The role of shape resonances and many-body effects on universal quantum sticking of ultra cold atoms onto solid surfaces is examined analytically and computationally using an exactly solvable representation of the Dyson equation.
Bittner, Eric R., Light, John C.
core   +1 more source

The Second Postulate of Relativity and the Electromagnetic Emission Theory of Light [PDF]

, 1911
Oscar M. Stewart
openalex   +1 more source

RAE Light

RAE: Revista de Administração de Empresas, 1994
HIGHLIGHT é um suplemento da RAE- Revista de Administração de Empresas da EAESP/FGV. Seu objetivo é divulgar o processo de renovação permanente por que passam as organizações com ênfase na ação de alunos, professores e ex-alunos da EAESP/FGV neste processo. Além disso, procura veicular notícias, opiniões e idéias que venham a contribuir com a difusão e
openaire   +30 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

The Evolution of EU policy towards its CIS neighbours [PDF]

When the EU began to plan enlargement, it was important to define and establish a new relationship with the successor states to the Soviet Union. This paper traces the evolution of the EU's policy towards those successor states from 1991 until the ...
Margot Light
core  

Finding a Future for Environmental Ethics [PDF]

Les Ateliers de l’Ethique, 2012
Andrew Light
doaj   +1 more source

Palaeoclimatic events, dispersal and migratory losses along the Afro-European axis as drivers of biogeographic distribution in Sylvia warblers

BMC Evolutionary Biology, 2011
Background The Old World warbler genus Sylvia has been used extensively as a model system in a variety of ecological, genetic, and morphological studies.
Light Jessica E, Voelker Gary
doaj   +1 more source

THE IDENTITY OF THE FLUORESCENT AND DELAYED LIGHT EMISSION SPECTRA IN CHLORELLA [PDF]

, 1954
William A. Arnold, J. B. Davidson
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source