Results 91 to 100 of about 17,219,574 (393)

Evidence for a heritable predisposition to Chronic Fatigue Syndrome

open access: yesBMC Neurology, 2011
Background Chronic Fatigue Syndrome (CFS) came to attention in the 1980s, but initial investigations did not find organic causes. Now decades later, the etiology of CFS has yet to be understood, and the role of genetic predisposition in CFS remains ...
Bateman Lucinda   +4 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Using HEC-FIA to identify Indirect Economic Losses

open access: yesE3S Web of Conferences, 2016
The United States Army Corps of Engineers’ Hydrologic Engineering Center developed the HEC-FIA (Flood Impact Analysis) software to assist in the estimation of consequences with uncertainty.
Lehman William, Light Miles
doaj   +1 more source

RAE Light

open access: yesRAE: Revista de Administração de Empresas, 1994
HIGHLIGHT é um suplemento da RAE- Revista de Administração de Empresas da EAESP/FGV. Seu objetivo é divulgar o processo de renovação permanente por que passam as organizações com ênfase na ação de alunos, professores e ex-alunos da EAESP/FGV neste processo. Além disso, procura veicular notícias, opiniões e idéias que venham a contribuir com a difusão e
openaire   +30 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Why Parents Play Favorites: Explanations for Unequal Bequests [PDF]

open access: yes
Economists have invested a great deal of effort in trying to understand the motivation for family transfers, yet recent empirical work testing the seemingly appealing models of altruism and exchange has led to decidedly mixed results.
Audrey Light, Kathleen McGarry
core   +3 more sources

Finding a Future for Environmental Ethics [PDF]

open access: yesLes Ateliers de l’Ethique, 2012
Andrew Light
doaj   +1 more source

Palaeoclimatic events, dispersal and migratory losses along the Afro-European axis as drivers of biogeographic distribution in Sylvia warblers

open access: yesBMC Evolutionary Biology, 2011
Background The Old World warbler genus Sylvia has been used extensively as a model system in a variety of ecological, genetic, and morphological studies.
Light Jessica E, Voelker Gary
doaj   +1 more source

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