Results 101 to 110 of about 13,240,817 (334)

Adventures in the Not Quite Yet: using performance techniques to raise design awareness about digital networks [PDF]

open access: yes, 2009
Technologists promise a future in which pervasive, distributed networks enable radical change to social and political geographies. Design of these abstract, intangible futures is difficult and carries a special risk of excluding people who are not ...
Healey, Pat, Light, Ann, Weaver, Lois
core  

The Social Context of Racial Boundary Negotiations: Segregation, Hate Crime, and Hispanic Racial Identification in Metropolitan America

open access: yesSociological Science, 2016
How the influx of Hispanics is reshaping the U.S. racial landscape is a paramount question in sociology. While previous research has noted the significant differences in Hispanics’ racial identifications from place to place, there are comparatively few ...
Michael T. Light, John Iceland
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Beyond enterprise resource planning projects: innovative strategies for competitive advantage [PDF]

open access: yes, 1999
A rapidly changing business environment and legacy IT problems has resulted in many organisations implementing standard package solutions. This 'common systems' approach establishes a common IT and business process infrastructure within organisations and
Holland, C, Kawalek, P, Light, BA
core   +1 more source

Error estimates for interpolation of rough data using the scattered shifts of a radial basis function

open access: yes, 2007
The error between appropriately smooth functions and their radial basis function interpolants, as the interpolation points fill out a bounded domain in R^d, is a well studied artifact. In all of these cases, the analysis takes place in a natural function
F.J. Narcowich   +8 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Rejection versus forceful imposition during elections: the ‘I have come to stay’ mindset of the incumbent

open access: yesHumanities & Social Sciences Communications
Political actors may resort to drastic measures, including election-related violence, to pursue electoral victory. While free and fair elections are fundamental to any democratic system, electoral violence threatens the integrity of this process and ...
Light Iwhuechiokike Nyeche
doaj   +1 more source

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