Results 81 to 90 of about 17,219,574 (393)

Network analysis of metabolic enzyme evolution in Escherichia coli

open access: yesBMC Bioinformatics, 2004
Background The two most common models for the evolution of metabolism are the patchwork evolution model, where enzymes are thought to diverge from broad to narrow substrate specificity, and the retrograde evolution model, according to which enzymes ...
Kraulis Per, Light Sara
doaj   +1 more source

Error estimates for interpolation of rough data using the scattered shifts of a radial basis function

open access: yes, 2007
The error between appropriately smooth functions and their radial basis function interpolants, as the interpolation points fill out a bounded domain in R^d, is a well studied artifact. In all of these cases, the analysis takes place in a natural function
F.J. Narcowich   +8 more
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Adventures in the Not Quite Yet: using performance techniques to raise design awareness about digital networks [PDF]

open access: yes, 2009
Technologists promise a future in which pervasive, distributed networks enable radical change to social and political geographies. Design of these abstract, intangible futures is difficult and carries a special risk of excluding people who are not ...
Healey, Pat, Light, Ann, Weaver, Lois
core  

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Reconfiguring Socialist Urban Landscapes: The ‘Left-Over’ Spaces of State-Socialism in Bucharest [PDF]

open access: yesHuman Geographies: Journal of Studies and Research in Human Geography, 2010
The end of state-socialism has produced complex processes of urban change in East and Central Europe including the reshaping of urban identities and urban cultural landscapes in post-socialist cities.
Duncan Light , Craig Young
doaj  

HIGHLIGHTING CHANGES IN TWO RUSSIAN SCHOOLS WITH SUCCESSFUL ONE-TO-ONE LAPTOP PROGRAMS: MOSCOW AND NIZHNY NOVGOROD CASE STUDIES

open access: yesОткрытое образование (Москва), 2016
One-to-one educational model of mobile learning at school is essential part of Innovative education reform and modernization of Russian educational system [1].
Daniel Light, Elizabeth Pierson
doaj   +1 more source

Beyond enterprise resource planning projects: innovative strategies for competitive advantage [PDF]

open access: yes, 1999
A rapidly changing business environment and legacy IT problems has resulted in many organisations implementing standard package solutions. This 'common systems' approach establishes a common IT and business process infrastructure within organisations and
Holland, C, Kawalek, P, Light, BA
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

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