Results 111 to 120 of about 8,570,567 (357)

CSF neurofilament light chain reflects corticospinal tract degeneration in ALS

Annals of Clinical and Translational Neurology, 2015
Diffusion tensor imaging (DTI) is sensitive to white matter tract pathology. A core signature involving the corticospinal tracts (CSTs) has been identified in amyotrophic lateral sclerosis (ALS).
R. Menke, E. Gray, Ching-Hua Lu, Jens Kuhle, K. Talbot, A. Malaspina, M. Turner   +6 more
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Effects of plasma-activated water on structural and functional properties of PSE-like chicken protein isolate

Current Research in Food Science
Pale, soft and exudative (PSE)-like chicken meat is rich in high-quality proteins, however, due to the properties of PSE-like meat, the functional characteristics of PSE-like chicken meat protein isolate (PPI) are affected.
Ke Li, Yanfang Zhou, Chenyan Zhu, Manting Du, Bo Chen, Dianbo Zhao, Yanhong Bai   +6 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Ultrasound-assisted immersion freezing improves the digestion properties of beef myofibrillar protein

Food Chemistry: X
This study focused on the effect of ultrasound-assisted immersion freezing (UIF) with different ultrasound power (200, 400, 600 W) on the physicochemical and in vitro digestive properties of beef myofibrillar proteins (BMP).
Junguang Li, Chenhao Sun, Xiaonan Yue, Wuchao Ma, Yu Wang, Jiansheng Zhao, Guangsu Zhu, Yanhong Bai   +7 more
doaj   +1 more source

Physiological Characteristics and Transcriptomic Analysis of Saccharomyces cerevisiae under Carvacrol Stress [PDF]

Shipin Kexue
This study investigated the effect of carvacrol stress on the physiological characteristics and transcriptome of Saccharomyces cerevisiae, a common spoilage yeast in fruit and vegetable products.
NIU Liyuan, SUN Xiaocheng, LIU Jingfei, WU Zihao, BAI Yanhong, ZHANG Zhijian
doaj   +1 more source

Fast and slow light in zig-zag microring resonator chains

, 2008
We analyze fast and slow light transmission in a zig-zag microring resonator chain. This novel device permits the operation in both regimes. In the superluminal case, a new ubiquitous light transmission effect is found whereby the input optical pulse is ...
Blair, Boyd, Boyd, F. J. Fraile-Pelaez, Fraile-Pelaez, Heebner, Khurgin, Khurgin, Liu, Morichetti, P. Chamorro-Posada, Parra, Scheuer, Uranus, Xia, Zirngibl   +15 more
core   +1 more source

Interaction of two photoreceptors in the regulation of bacterial photosynthesis genes [PDF]

, 2012
The expression of photosynthesis genes in the facultatively photosynthetic bacterium Rhodobacter sphaeroides is controlled by the oxygen tension and by light quantity. Two photoreceptor proteins, AppA and CryB, have been identified in the past, which are
Frühwirth, Sebastian, Haberzettl, Kerstin, Hasewinkel, Christian, Klug, Gabriele, Metz, Sebastian, Teich, Kristin   +5 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Anthocyanin-loaded complexes of glycated dual milk-derived proteins: thermal stability, storage stability, and simulated digestion

Ultrasonics Sonochemistry
Anthocyanin (ACN) have attracted considerable scholarly attention owing to exceptional biological activities. Nonetheless, their limited stability and bioavailability present significant challenges to practical applications.
Shuangshuang Wang, Zhenzhu Li, Qingshuang Qiu, Huilin Lv, Haokun Zhang, Hang Wang, Rongzu Nie, Wupeng Ge, Peifeng Li   +8 more
doaj   +1 more source