Results 171 to 180 of about 8,570,567 (357)

[Efficacy and safety of daratumumab in the treatment of advanced light chain amyloidosis].

, 2022
K.-N. Shen, H.L Miao, Y. J. Gao, X.X. Cao, D B Zhou, W. Su, J. Li   +6 more
openalex   +2 more sources

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

Primary structure of a human IgA1 immunoglobulin. V. Amino acid sequence of a human IgA lambda light chain (Bur).

, 1979
A. J. Infante, Putnam Fw
openalex   +1 more source

Paclitaxel Treatment Effects on Neurofilament Light Chain (NF-L), a Possible Biomarker of Chemotherapy-Induced Peripheral Neuropathy (CIPN) [PDF]

, 2022
LW Benashley, AM Bucy, BC Wertheim, R Blew, P Chalasani, C Thomson, JW Bea   +6 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Combined use of free light chain and heavy/light chain ratios allow diagnosis and monitoring of patients with monoclonal gammopathies: Experience of a single institute, with three exemplar case reports

, 2016
Gagliardi, Alfredo, Carbone, Claudio, Russo Angela, Cuccurullo, Rosanna, Lucania, Anna, Cioppa, Paola Della, Misso Gabriella, Caraglia Michele, Tommasino, Catello, Mastrullo, Lucia   +9 more
openalex   +2 more sources

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Preparation and Performance Evaluation of Polysaccharide–Iron Complex of Eucommia ulmoides

Foods
An innovative iron supplement crucial for treating iron-deficiency anemia was developed in this study. Polysaccharide was extracted from Eucommia ulmoides leaves using a microwave-assisted hot water method, and subsequently, the polysaccharide–iron ...
Mengpei Liu, Yan Wang, Rong Wang, Wei Zong, Lihua Zhang, Lu Wang   +5 more
doaj   +1 more source

Effect of phosphorylation of myosin light chain by myosin light chain kinase and protein kinase C on conformational change and ATPase activities of human platelet myosin [PDF]

, 1991
Higashihara M, K. Takahata, K. Kurokawa
openalex   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

Advanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source