Results 81 to 90 of about 35,531 (245)

Negative for AL and ATTR: Could It Still Be Amyloid?

Annals of Internal Medicine: Clinical Cases
Amyloidosis is a systemic disease characterized by the extracellular deposition of misfolded proteins. We present a rare case of familial amyloidosis with multiorgan involvement.
Ahmed B. Elawad, Paul Wilkinson, Ryan Kimball, Ahmed F. Abdulrahim   +3 more
doaj   +1 more source

Apolipoprotein C-II Deposition Amyloidosis: A Potential Misdiagnosis as Light Chain Amyloidosis

Case Reports in Nephrology, 2016
Hereditary amyloidoses are rare and pose a diagnostic challenge. We report a case of hereditary amyloidosis associated with apolipoprotein C-II deposition in a 61-year-old female presenting with renal failure and nephrotic syndrome misdiagnosed as light ...
Sadichhya Lohani, Emily Schuiteman, Lohit Garg, Dhiraj Yadav, Sami Zarouk   +4 more
doaj   +1 more source

Light chain type predicts organ involvement and survival in AL amyloidosis patients receiving stem cell transplantation

Blood Advances, 2018
: We evaluated the impact of light chain type, lambda (λ) or kappa (κ), on disease features and outcomes in patients with immunoglobulin light chain (AL) amyloidosis receiving stem cell transplant at the Mayo Clinic between October 2002 and August 2016 ...
M Hasib Sidiqi, Mohammed A. Aljama, Eli Muchtar, Francis K. Buadi, Rahma Warsame, Martha Q. Lacy, Angela Dispenzieri, David Dingli, Nelson Leung, Wilson I. Gonsalves, Shaji K. Kumar, Prashant Kapoor, Taxiarchis V. Kourelis, William J. Hogan, Morie A. Gertz   +14 more
doaj   +1 more source

Left ventricular transthyretin amyloid load and apical sparing in patients with newly confirmed transthyretin amyloid cardiomyopathy

European Journal of Heart Failure, EarlyView.
In a large cohort of patients with newly diagnosed transthyretin amyloid cardiomyopathy (ATTR‐CM), echocardiographic apical sparing was associated with increased left ventricular amyloid load and atrial remodelling. Quantitative biopsy analysis revealed that Perugini scores often failed to accurately reflect myocardial amyloid burden.
Thomas Krammer, Maria J. Baier, Vanessa Lutz, Anna‐Christina Hübner, Tilman Zschiedrich, David Lukas, Christian Le Phu, Matthias Wolf, Claire Maassen, Michael Wester, Stefan Neef, Christian Schach, Can‐Martin Sag, Katja Evert, Michael Paulus, Christine Meindl, Maria Tafelmeier, Kurt Debl, Lars S. Maier, Stefan Wagner, Christoph Röcken, Julian Mustroph   +21 more
wiley   +1 more source

Historic characteristics and mortality of patients in the Swiss Amyloidosis Registry

Swiss Medical Weekly
AIMS OF THE STUDY: Systemic amyloidoses are rare protein-folding diseases with heterogeneous, often nonspecific clinical presentations. To better understand systemic amyloidoses and to apply state-of-the-art diagnostic pathways and treatment, the ...
Sofie Brouwers, Raphael Heimgartner, Natallia Laptseva, Adriano Aguzzi, Niklas F. Ehl, Thomas Fehr, Felicitas Hitz, Hans H. Jung, Joel Kälin, Markus G. Manz, Beat Müllhaupt, Frank Ruschitzka, Harald Seeger, Georg Stussi, Markus Zweier, Andreas J. Flammer, Bernhard Gerber, Rahel Schwotzer   +17 more
doaj   +1 more source

Amiloidose renal: classificação de 102 casos consecutivos [PDF]

, 2014
Amyloidoses are a group of heterogeneous diseases classified according to the nature of their causative amyloid proteins. Commonly, paraffin-embedded tissue is used for the typing of amyloid by immunohistochemistry.
Lobato, L., Moreira, L., Oliveira, J., Pereira, P., Pinho-Costa, P., Sampaio, S., Tavares, I., Vaz, R., Vizcaíno, J.   +8 more
core  

Comparison of Two Strategies of Analysis of Urinary Protein Composition for the Diagnosis and Follow‐Up of Renal Diseases

ELECTROPHORESIS, EarlyView.
ABSTRACT Proteinuria analysis is necessary to detect the early stages of kidney disease before the estimated glomerular filtration rate deteriorates and to monitor the progression of treated kidney disease. Electrophoresis is often the first orientation test, although this test is time‐consuming and its interpretation may be subjective.
Joris Guyon, Jeanne Malaubier, Hong‐Van Pham, Lila Rami Arab, Laurence Pieroni, Marie‐Laure Curutchet‐Burtin, Rémi Segues, Sylvie Caspar‐Bauguil, Annie M. Bérard   +8 more
wiley   +1 more source

Case Report: Left bundle branch pacing in an amyloid light-chain cardiac amyloidosis patient with atrioventricular block

Frontiers in Cardiovascular Medicine
IntroductionAmyloid light-chain cardiac amyloidosis is a progressive infiltrative disease characterized by the deposition of amyloid fibrils in the cardiac tissue, which can cause serious atrioventricular block requiring pacemaker implantation.
Jiaqi Yu, Fanyi Kong, Peng Gao, Taibo Chen, Yongtai Liu, Zhongwei Cheng, Hua Deng, Jinzhi Lai, Lihua Zhang, Jingbo Fan, Jiaqi Wang, Xiaohan Qin, Keyue Sun, Jian Li, Quan Fang, Deyan Yang, Kang’an Cheng   +16 more
doaj   +1 more source

Virtual Screening for Promising Kinetic Stabilizers of Light Chains in Immunoglobulin Light Chain Amyloidosis Through Drug Repurposing [PDF]

, 2023
Jonas Jeppesen, Casper Steinmann
openalex   +1 more source

Infertility and hypergonadotropic hypogonadism as first evidence of hereditary apolipoprotein A-I amyloidosis [PDF]

, 2007
Purpose: We report that primary infertility and hypergonadotropic hypogonadism in young patients may be caused by testicular amyloidosis and it is associated with the presence of a mutation in the apoA-I gene, resulting in the replacement of proline for ...
BIASI L, F. SCOLARI, GREGORINI G, MARTINI PR, MERLINI G, OBICI L, SCALVINI T, TARDANICO R   +7 more
core   +1 more source