Results 41 to 50 of about 5,923,968 (244)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Classification of Mira variables based on visual light curve shape

open access: yes, 1988
We have classified 368 Mira variables of M, S and C spectral classes based on the shape of their visual light curve. The classification is esentially based on Ludendorff's (1928) scheme and the light curves used are mainly from the compilation of ...
Vardya, M. S.
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

An Evenly Spaced LSST Cadence for Rapidly Variable Stars

open access: yesThe Astrophysical Journal Supplement Series, 2023
Stars exhibit a bewildering variety of rapidly variable behaviors ranging from explosive magnetic flares to stochastically changing accretion to periodic pulsations or rotation.
Eric D. Feigelson   +2 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Deep Attention-based Supernovae Classification of Multiband Light Curves

open access: yesThe Astronomical Journal, 2022
In astronomical surveys, such as the Zwicky Transient Facility, supernovae (SNe) are relatively uncommon objects compared to other classes of variable events. Along with this scarcity, the processing of multiband light curves is a challenging task due to
Óscar Pimentel   +2 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Light-Curve Classification of Resident Space Objects for Space Situational Awareness: A Scoping Review

open access: yesAerospace
The proliferation of Resident Space Objects (RSOs), including satellites, rocket bodies, and debris, poses escalating challenges for Space Situational Awareness (SSA). Optical light curves capture temporal brightness variations influenced by factors such
Minyoung Hwang   +4 more
doaj   +1 more source

Machine learning methods for fission product identification from Bragg curves

open access: yesAIP Advances, 2023
A fission time projection chamber (fission-TPC) was developed to provide precise neutron-induced fission measurements for several major actinides. As fission fragments lose energy in one of the gas volumes of the fission-TPC, energy loss information is ...
S. M. Lyons   +6 more
doaj   +1 more source

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