Results 41 to 50 of about 154,240 (279)

Light-curve classification in massive variability surveys -- I. Microlensing [PDF]

Monthly Notices of the Royal Astronomical Society, 2003
This paper exploits neural networks to provide a fast and automatic way to classify light curves in massive photometric data sets. As an example, we provide a working neural network that can distinguish microlensing light curves from other forms of variability, such as eruptive, pulsating, cataclysmic and eclipsing variable stars.
V. Belokurov, N. W. Evans, Y. L. Du
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The Impact of Host-galaxy Properties on Supernova Classification with Hierarchical Labels

The Astrophysical Journal Supplement Series
With the advent of the Vera C. Rubin Observatory, the discovery rate of supernovae (SNe) will surpass the rate of SNe with real time spectroscopic follow-up by 3 orders of magnitude.
V. Ashley Villar, Sebastian Gomez, Edo Berger, Alex Gagliano   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

An Evenly Spaced LSST Cadence for Rapidly Variable Stars

The Astrophysical Journal Supplement Series, 2023
Stars exhibit a bewildering variety of rapidly variable behaviors ranging from explosive magnetic flares to stochastically changing accretion to periodic pulsations or rotation.
Eric D. Feigelson, Federica B. Bianco, Rosaria Bonito   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Machine learning methods for fission product identification from Bragg curves

AIP Advances, 2023
A fission time projection chamber (fission-TPC) was developed to provide precise neutron-induced fission measurements for several major actinides. As fission fragments lose energy in one of the gas volumes of the fission-TPC, energy loss information is ...
S. M. Lyons, C. G. Britt, L. S. Wood, D. L. Duke, B. G. Fulsom, M. E. Moore, L. Snyder   +6 more
doaj   +1 more source

Automatic classification of eclipsing binaries light curves using neural networks

, 2006
In this work we present a system for the automatic classification of the light curves of eclipsing binaries. This system is based on a classification scheme that aims to separate eclipsing binary systems according to their geometrical configuration in
Á. Giménez, C. Sánchez-Fernández, L. M. Sarro   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

General classification of light curves using extreme boosting

, 2019
A significant degree of misclassification of variable stars through the application of machine learning methods to survey data motivates a search for more reliable and accurate machine learning procedures, especially in light of the very large data cubes that will be generated by future surveys and the need for immediate production of accurate ...
Kgoadi, Refilwe, Engelbrecht, Chris, Whittingham, Ian, Tkachenko, Andrew   +3 more
openaire   +2 more sources