Results 61 to 70 of about 154,240 (279)

PELICAN: deeP architecturE for the LIght Curve ANalysis

, 2019
[Departement_IRSTEA]Territoires [TR1_IRSTEA]SYNERGIEInternational audienceWe developed a deeP architecturE for the LIght Curve ANalysis (PELICAN) for the characterization and the classification of light curves. It takes light curves as input, without any
Fouchez, Dominique, Johanna Pasquet, Itam-Pasquet, Johanna, Chaumont, Marc, Dominique Fouchez, Marc Chaumont, Pasquet, Jérôme, Jérôme Pasquet   +7 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Unsupervised classification of eclipsing binary light curves throughk-medoids clustering [PDF]

Journal of Applied Statistics, 2019
This paper proposes k-medoids clustering method to reveal the distinct groups of 1,318 variable stars in the Galaxy based on their light curves, where each light curve represents the graph of brightness of the star against time. To overcome the deficiencies of subjective traditional classification, we separate the stars more scientifically according to
Modak, Soumita, Chattopadhyay, Tanuka, Chattopadhyay, Asis Kumar   +2 more
openaire   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Discovery and Detailed Study of the M31 Classical Nova AT 2023tkw: Evidence for Internal Shocks

The Astrophysical Journal
We present a detailed analysis of an extragalactic slow classical nova in M31 exhibiting multiple peaks in its light curve. Spectroscopic and photometric observations were used to investigate the underlying physical processes.
Judhajeet Basu, Ravi Kumar, G.C. Anupama, Sudhanshu Barway, Peter H. Hauschildt, Shatakshi Chamoli, Vishwajeet Swain, Varun Bhalero, Viraj Karambelkar, Mansi Kasliwal, Kaustav K. Das, Igor Andreoni, Avinash Singh, Rishabh Singh Teja   +13 more
doaj   +1 more source

Sparse Logistic Regression for RR Lyrae versus Binaries Classification

The Astrophysical Journal, 2023
RR Lyrae (RRL) stars are old, low-mass, radially pulsating variable stars in their core helium burning phase. They are popular stellar tracers and primary distance indicators since they obey well-defined period–luminosity relations in the near-infrared ...
Piero Trevisan, Mario Pasquato, Gaia Carenini, Nicolas Mekhaël, Vittorio F. Braga, Giuseppe Bono, Mohamad Abbas   +6 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

THE MATHEMATICAL MODEL OF THE PHOTOMETRIC VARIABILITY AND CLASSIFICATION OF SEMIREGULAR PULSATING ASYMPTOTIC GIANTS BRANCH STARS

Odessa Astronomical Publications, 2012
The modern review of the stars which are located at the position of asymptotic giant branch at the HRdiagram is presented. The most interesting problems connected to these objects are noted, as well as attention is paid to classification and to the ...
L. S. Kudashkina
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Deep Learning and Methods Based on Large Language Models Applied to Stellar Light Curve Classification

Intelligent Computing
Light curves serve as a valuable source of information on stellar formation and evolution. With the rapid advancement of machine learning techniques, they can be effectively processed to extract astronomical patterns and information.
Yu-Yang Li, Yu Bai, Cunshi Wang, Mengwei Qu, Ziteng Lu, Roberto Soria, Jifeng Liu   +6 more
doaj   +1 more source