Results 51 to 60 of about 5,923,968 (244)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Superphot+: Real-time Fitting and Classification of Supernova Light Curves

open access: yesThe Astrophysical Journal
Photometric classifications of supernova (SN) light curves have become necessary to utilize the full potential of large samples of observations obtained from wide-field photometric surveys, such as the Zwicky Transient Facility (ZTF) and the Vera C ...
Kaylee M. de Soto   +11 more
doaj   +1 more source

Classification of Exoplanetary Light Curves Using Artificial Intelligence

open access: yesAI
In this article, we propose a robust star classification methodology leveraging light curves collected from 15 datasets within the Kepler field in the visible optical spectrum.
Leticia Flores-Pulido   +3 more
doaj   +1 more source

Outside Curve.

open access: yes, 2014
A 2 minute sound recording of passersby outside ...
Hill, Andrew
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Discovery and Detailed Study of the M31 Classical Nova AT 2023tkw: Evidence for Internal Shocks

open access: yesThe Astrophysical Journal
We present a detailed analysis of an extragalactic slow classical nova in M31 exhibiting multiple peaks in its light curve. Spectroscopic and photometric observations were used to investigate the underlying physical processes.
Judhajeet Basu   +13 more
doaj   +1 more source

Curve, 2012

open access: yes, 2012
Colour photograph of the completed Curve which looms large next to the older buildings of the ...
Hyde, Colin;
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Curve Theatre interior.

open access: yes, 2014
Colour photograph of the interior of the Curve Theatre, Leicester, showing lighting equipment in the stage ...
Barnes, Amy
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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