Results 151 to 160 of about 1,812,631 (345)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Generalized Bertrand Curves of Non-Light-like Framed Curves in Lorentz–Minkowski 3-Space

Mathematics
In this paper, we define the generalized Bertrand curves of non-light-like framed curves in Lorentz–Minkowski 3-space; their study is essential for understanding many classical and modern physics problems.
Linlin Wu, Anjie Zhou, Kaixin Yao, Donghe Pei   +3 more
doaj   +1 more source

Breaking the Degeneracy in Magnetic Cataclysmic Variable X-Ray Spectral Modeling Using X-Ray Light Curves [PDF]

, 2021
Diogo Belloni, C. V. Rodrigues, M. R. Schreiber, Manuel Castro, J. E. R. Costa, Takayuki Hayashi, I. J. Lima, G. J. M. Luna, Murilo Martins, A. S. Oliveira, S. G. Parsons, K. M. G. Silva, Paulo E. Stecchini, T. J. Stuchi, M. Zorotovic   +14 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Photometric Study of Extreme Long Period Eclipsing Binary 31 CYG [PDF]

Journal of Astronomy and Space Sciences, 1991
The UBV light curves of an extreme long period binary star 31 Cyg are made with the observations obtained at Yonsei University Observatory for three seasons from 1988 to 1991 and the RI light curves are also made for one season in 1990-1991.
Jang Hae Jeong, Yong-Sam Lee, Ho-Il Kim
doaj  

Linking Anomalous Behaviour with Stellar Properties: An Unsupervised Exploration of TESS Light Curves [PDF]

, 2023
Dennis Crake, Juan Rafael Martínez-Galarza   +1 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Typical X-Ray Outburst Light Curves of Aql X-1

The Astrophysical Journal
We show that the typical X-ray outburst light curve of Aql X-1 can be reproduced by accretion onto a neutron star in the frame of the disk instability model without invoking partial accretion or the propeller effect.
Ömer Faruk Çoban, Ünal Ertan
doaj   +1 more source

Dynamical Evolution, Light Curves, and Spectra of Spherical and Collimated Gamma‐Ray Burst Remnants [PDF]

, 1999
A. Panaitescu, P. Meszaros
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source