Results 81 to 90 of about 413,490 (265)
The Statistical Study of the Daily Fermi Light Curves of 130 Sources
Galaxies, 2017 Blazars show rapid and high amplitude variability. It is interesting to question what kind of process the variability corresponds to. Maybe it is a result of the instability of the accretion flows.
Wei Cai, Yi Liu, Jun H. Fan
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Extinction and Scattering of Light by Magnetic Colloidal Nanoparticles [PDF]
Журнал нано- та електронної фізики, 2015 The peculiarities of scattering and extinction of light by colloids with different concentrations of magnetite nanoparticles are investigated. The light absorption effect on spectral dependencies of optical density of magnetic colloid are observed ...
C.V. Yerin
doaj
EPJ Web of Conferences, 2016 The past decade has provided a much clearer picture of the structure of high-momentum components in nucleons, associated with hard, short-distance interactions between pairs of nucleons.
Arrington John
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Elastic scattering and total reaction cross sections with low-energy light radioactive ion beams.
EPJ Web of Conferences, 2011 Elastic scattering experiments have being performed with low-energy radioactive ion beams produced by the RIBRAS facility in Sao Paulo, Brazil. Here I present the results for elastic scattering of 6He on several targets and light beams on 12C target ...
Guimarães Valdir
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source