Results 91 to 100 of about 849,538 (300)

Highly efficient and wide-color-gamut organic light-emitting devices using external microcavity

Journal of Information Display, 2019
An external microcavity structure was introduced to the stacked cathode in organic light-emitting devices (OLEDs), and its influence on the luminescent characteristics was investigated.
Akiyoshi Mikami
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Revealing the Role of Sidewall Orientation in Wet Chemical Etching of GaN-Based Ultraviolet Light-Emitting Diodes

Nanomaterials, 2019
We demonstrated that the tetramethylammonium hydroxide (TMAH) solution possesses different etching abilities to the chip sidewalls with different orientations because the orientation of chip sidewall determines the exposed crystallographic plane of ...
Hui Wan, Bin Tang, Ning Li, Shengjun Zhou, Chengqun Gui, Sheng Liu   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Improved light extraction efficiency of GaN-based flip-chip light-emitting diodes with an antireflective interface layer

, 2016
GaN-based flip-chip light-emitting diodes (FC-LEDs) grown on nanopatterned sapphire substrates (NPSS) are fabricated using self-assembled SiO2 nanospheres as masks during inductively coupled plasma etching.
Boting Liu, Shuo Zhang, Jinmin Li, Junxi Wang, Dongxue Wu, Ping Ma   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Porous cellulose paper as a light out coupling medium for organic light-emitting diodes

Journal of Information Display, 2018
Porous nanocellulose paper was fabricated and applied as a light outcoupling medium. The nanocellulose papers were prepared using cellulose powder and a high-pressure homogenizing process.
Jeong Hun Lee, Sohyeon Kang, Nae-Man Park, Jin-Wook Shin, Chul Woong Joo, Jonghee Lee, Seong-Deok Ahn, Seung-Youl Kang, Jaehyun Moon   +8 more
doaj   +1 more source

Multiscale Laser Written Photonic Structures in Bulk Chalcogenide Glasses for Infrared Light Transport and Extraction

, 2021
International audienceDirect ultrafast laser processing is nowadays considered the most flexible technique allowing to generate complex 3D optical functions in bulk glasses.
Guanghua Cheng, Guillermo Martin, D’amico, Ciro, Cheng, Guanghua, Ciro D’Amico, Martin, Guillermo, Stoian, Razvan, Troles, Johann, Johann Troles, Razvan Stoian   +9 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source