Results 121 to 130 of about 8,681,014 (339)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Geometric spin Hall effect of light in tightly focused polarization tailored light beams
, 2013 Recently, it was shown that a non-zero transverse angular momentum manifests itself in a polarization dependent intensity shift of the barycenter of a paraxial light beam [A. Aiello et al., Phys. Rev. Lett. 103, 100401 (2009)].
Aiello, Andrea +6 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Readout system for radiation detector [PDF]
, 1968 Improved electrical circuit determines the amount of light detected by a photomultiplier tube when its output signal is in the dark-current range of the tube.
Baker, B. R., Cashion, K. D.
core +1 more source
Molecules, 2016 Epimedium pseudowushanense B.L.Guo is used in traditional medicine as an aphrodisiac and to strengthen muscles and bones. Several recent reports have shown that flavonoids from Epimedium also significantly affect the treatment of breast cancer, liver ...
Junqian Pan, B. Guo
semanticscholar +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Light intensity of 5 or 20 lux on broiler behavior, welfare and productivity
Poultry Science, 2016 &NA; Light intensity can influence broiler behavior, but discrepancies in the scientific literature remain. Furthermore, few studies have investigated the welfare implications induced by varying light intensity. We investigated the effects of providing 5
J. Rault +3 more
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Agronomy‘Shine muscat’ grapevines must be cultivated in a protected facility to avoid insects and rain during the rainy season; however, this decreases the light intensity falling on the canopy of grapes.
Yu Yuan +5 more
doaj +1 more source
Real time pre-detection dynamic range compression [PDF]
, 1992 A real time, pre-detection optical dynamic range compression system uses a photorefractive crystal, such as BaTiO3 or LiNbO3, in which light induced scattering from crystal inhomogeneities of the optical input occurs as a nonlinear function of the input ...
Liu, Hua-Kuang
core +1 more source