Results 81 to 90 of about 5,738,233 (301)
, 2014 Extracellular polymeric substances (EPS) acting as cementing substance (chelator) of biological soil crusts (BSCs) are a considerable amount of metabolic investment for cyanobacteria. However, their partition mechanism has long been overlooked.
Xia, Ling +5 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Light-Intensity Physical Activity and Cardiometabolic Biomarkers in US Adolescents
, 2013 Background: The minimal physical activity intensity that would confer health benefits among adolescents is unknown. The purpose of this study was to examine the associations of accelerometer-derived light-intensity (split into low and high) physical ...
B. Howard (11323596) +7 more
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
STUDY OF THE INTENSITY OF THE LIGHT FLOW OF DENTAL PHOTOPOLYMERIZERS
Український стоматологічний альманахRelevance. During the direct restoration of teeth with light-curing composites, it is important to irradiate them from the minimum distance to ensure a sufficient amount of light energy for curing, but this is not always achievable. Objective.
O.A. Udod +2 more
doaj +1 more source
Influence of light intensity on plasma melatonin and locomotor activity rhythms in tench
, 2005 Melatonin production by the pineal organ is influenced by light intensity, as has been described in most vertebrate species, in which melatonin is considered a synchronizer of circadian rhythms.
Sanchez-Vazquez, F Javier +4 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Light‐Intensity Switching of Graphene/WSe2 Synaptic Devices
Advanced Science2D van der Waals heterojunctions (vdWH) have emerged as an attractive platform for the realization of optoelectronic synaptic devices, which are critical for energy‐efficient computing systems. Photogating induced by charge traps at the interfaces indeed
Hongyu Tang +3 more
doaj +1 more source
Padjadjaran Journal of Dentistry, 2018 Introduction: Composite-resin is widely used as a restorative material in dental practice on a daily basis when it comes to an aesthetic consideration.
Henri Hartman
doaj +1 more source