Results 61 to 70 of about 5,682 (253)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Fish Suppressors of Cytokine Signaling (SOCS) : Gene Discovery, Modulation of Expression and Function [PDF]
, 2011 Peer ...
Gorgoglione, Bartolomeo +13 more
core +1 more source
Sensing the light: photoreceptive systems and signal transduction in cyanobacteria [PDF]
Molecular Microbiology, 2007 SummaryPhotosynthetic prokaryotes have highly developed abilities to detect and react to environmental signals. Light sensing is one of the most important capabilities of organisms that use light for photosynthesis and photomorphogenesis. This review addresses photoreception in cyanobacteria from the perception of light through the physiological ...
openaire +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Light matters: phototaxis and signal transduction in unicellular cyanobacteria [PDF]
Molecular Microbiology, 2004 SummaryMany photosynthetic microorganisms have evolved the ability to sense light quality and/or quantity and can steer themselves into optimal conditions within the environment. Phototaxis and gliding motility in unicellular cyanobacteria require type IV pili, which are multifunctional cell surface appendages.
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The BES1/BZR1 family transcription factor as critical regulator of plant stress resilience
Plant StressBrassinosteroids (BR) are ubiquitous polyhydroxylated steroid hormones in plants that play a pivotal role in orchestrating plant growth, development, and stress mitigation.
Long Li +7 more
doaj +1 more source
Redox Regulation of a Light-Harvesting Antenna Complex in an Anoxygenic Phototroph
mBio, 2019 The purple nonsulfur bacterium Rhodopseudomonas palustris is a model for understanding how a phototrophic organism adapts to changes in light intensity because it produces different light-harvesting (LH) complexes under high light (LH2) and low light ...
Kathryn R. Fixen +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Structural insight into PIF6-mediated red light signal transduction of plant phytochrome B
Cell DiscoveryThe red/far-red light receptor phytochrome B (phyB) plays essential roles in regulating various plant development processes. PhyB exists in two distinct photoreversible forms: the inactive Pr form and the active Pfr form.
Hanli Jia +9 more
doaj +1 more source