Results 101 to 110 of about 4,134,739 (261)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

An integrative model for phytochrome B mediated photomorphogenesis:from protein dynamics to physiology [PDF]

, 2010
Plants have evolved various sophisticated mechanisms to respond and adapt to changes of abiotic factors in their natural environment. Light is one of the most important abiotic environmental factors and it regulates plant growth and development ...
Nagy, Ferenc, Fleck, Christian, Julia Rausenberger, Hussong, Andrea, Stefan Kircher, Kirchenbauer, Daniel, Kirchenbauer Daniel, Hussong Andrea, Ferenc Nagy, Rausenberger, Julia, Schäfer, Eberhard, Andrea Hussong, Timmer, Jens, Rausenberger Julia, Timmer Jens, Kircher Stefan, Eberhard Schäfer, Schäfer Eberhard, Christian Fleck, Daniel Kirchenbauer, Nagy Ferenc, Fleck Christian, Kircher, Stefan, Jens Timmer   +23 more
core   +2 more sources

The FHY3/FAR1 Gene Family in Plants: Transposase-Derived Transcription Factors as Master Integrators of Light Signaling and Plant Development

Plants
The FAR-RED IMPAIRED RESPONSE 1 (FAR1) and FAR-RED ELONGATED HYPOCOTYL 3 (FHY3) transcription factors, together with other members of the FAR1-RELATED SEQUENCE (FRS) and FRS-RELATED FACTOR (FRF) families, represent a striking example of transposable ...
Hao Li, Lan Wei, Conghao Hong, Qingqing Huang, Zhimin Huang, Hongbo Gao   +5 more
doaj   +1 more source

Beyond Light: Insights Into the Role of Constitutively Photomorphogenic1 in Plant Hormonal Signaling

Frontiers in Plant Science, 2019
Light is an important environmental factor with profound effects in plant growth and development. Constitutively photomorphogenic1 (COP1) is a vital component of the light signaling pathway as a negative regulator of photomorphogenesis. Although the role
Wenjing Wang, Wenjing Wang, Qingbin Chen, Qingbin Chen, José Ramón Botella, Siyi Guo, Siyi Guo   +6 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium

, 2020
Compartmentalization of diverse types of signaling molecules contributes to the precise coordination of signal propagation. The primary cilium fulfills this function by acting as a spatiotemporally confined sensory signaling platform.
Pia Aanstad, Omar Torres-Quesada, Philipp Tschaikner, Eduard Stefan, Florian Enzler   +4 more
core   +1 more source

Surface plasmon polariton modification in top-emitting organic light-emitting diodes for enhanced light outcoupling [PDF]

, 2014
We report on the enhanced light outcoupling efficiency of monochrome top-emitting organic light-emitting diodes (OLEDs). These OLEDs incorporate a hole transport layer (HTL) material with a substantially lower refractive index (∼ 1:5) than the emitter ...
Hofmann, S., Gather, M.C., Simone Hofmann, Schwab, T., Malte C. Gather, Martin Wieczorek, Leo, K., Wieczorek, M., Reinhard Scholz, Fuchs, C., Cornelius Fuchs, Karl Leo, Scholz, R., Tobias Schwab   +13 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source