Results 21 to 30 of about 4,134,739 (261)

Hedgehog Signaling in Cortical Development [PDF]

, 2023
The Hedgehog (Hh) pathway plays a crucial role in embryonic development, acting both as a morphogenic signal that organizes tissue formation and a potent mitogenic signal driving cell proliferation.
Xuecai Ge, Cai, Eva, Ge, Xuecai, Maximiliano Gonzalez Barba, Barba, Maximiliano Gonzalez, Eva Cai   +5 more
core   +1 more source

Profiling DNA damage response following mitotic perturbations

Nature Communications, 2016
DNA damage arising from replication stress is well studied, but the effect of mitotic errors on genome integrity is less understood. Here the authors knock down 47 mitotic regulators and record how they impact on DNA breakage events, providing a resource
Ronni S. Pedersen, Gopal Karemore, Thorkell Gudjonsson, Maj-Britt Rask, Beate Neumann, Jean-Karim Hériché, Rainer Pepperkok, Jan Ellenberg, Daniel W. Gerlich, Jiri Lukas, Claudia Lukas   +10 more
doaj   +1 more source

The HY5-PIF regulatory module coordinates light and temperature control of photosynthetic gene transcription [PDF]

, 2014
The ability to interpret daily and seasonal alterations in light and temperature signals is essential for plant survival. This is particularly important during seedling establishment when the phytochrome photoreceptors activate photosynthetic pigment ...
Stewart, Kelly L., Karen J. Halliday (561241), Toledo Ortiz, Gabriela, Stewart, Kelly, Bou Torrent, Jordi, Keun Pyo Lee (577334), Gabriela Toledo-Ortiz, Lee, Keun Pyo, Gavin Steel, Karen J Halliday, Steel, Gavin, Keun Pyo Lee, Jordi Bou-Torrent (204117), Gavin Steel (577336), Toledo-Ortiz, Gabriela, Rodríguez-Concepción, Manuel, Manuel Rodríguez-Concepción (2185861), Jordi Bou-Torrent, Kelly Stewart, Henrik Johansson (519182), Halliday, Karen J., Henrik Johansson, Halliday, Karen J, Manuel Rodríguez-Concepción, Johansson, Henrik, Bou-Torrent, Jordi, Karen J. Halliday, Gabriela Toledo-Ortiz (577333), Rodríguez Concepción, Manuel, Kelly Stewart (577335)   +29 more
core   +1 more source

LIGHT/LTβR signaling regulates self-renewal and differentiation of hematopoietic and leukemia stem cells. [PDF]

, 2021
The production of blood cells during steady-state and increased demand depends on the regulation of hematopoietic stem cell (HSC) self-renewal and differentiation.
Raykova, Ana, Höpner, S. S., Radpour, R., Ochsenbein, A. F., Koller, D., Riether, C., Bärlocher, G. M., Amrein, M. A.   +7 more
core   +2 more sources

Basic Protein Modules Combining Abscisic Acid and Light Signaling in Arabidopsis

Frontiers in Plant Science, 2022
It is generally accepted that plants use the complex signaling system regulated by light and abscisic acid (ABA) signaling components to optimize growth and development in different situations.
Victor P. Bulgakov, Olga G. Koren
doaj   +1 more source

Alternate transcription of the Toll-like receptor signaling cascade [PDF]

, 2006
Alternate splicing of key signaling molecules in the Toll-like receptor (Tlr) cascade has been shown to dramatically alter the signaling capacity of inflammatory cells, but it is not known how common this mechanism is. We provide transcriptional evidence
Kai, Chikatoshi, Forrest, A, Schroder, K, Forrest, Alistair, Kawai, J, Kawaji, H, Wells, Christine A, Faulkner, G, Carninci, P, Hume, DA, Carninci, Piero, Grimmond, SM, Himes, SR, Lo, Sandra, Hume, David, Schroder, Kate, Taylor, D, Grimmond, Sean M, Faulkner, Geoffrey, Chalk, Alistair, Kasukawa, T, Himes, S Roy, Grimmond, Sean, Kawai, Jun, Waddell, Nic, Lo, Yu-Lan Sandra, Hayashizaki, Yoshihide, Kasukawa, Takeya, Wells, Christine, Katayama, S, Hayashizaki, Y, Chalk, Alistair M, Katayama, Shintaro, Hume, David A, Chalk, AM, Taylor, Darrin, Kawaji, Hideya, Wells, CA, Waddell, N, Lo, S, Kai, C   +40 more
core   +1 more source

A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells [PDF]

, 2013
Growth and differentiation of multicellular systems is orchestrated by spatially restricted gene expression programs in specialized subpopulations. The targeted manipulation of such processes by synthetic tools with high-spatiotemporal resolution could ...
Metzger, Stéphanie, Busacker, Moritz, Engesser, Raphael, Kämpf, Michael M., Nagy, Ferenc István, Müller, Konrad   +5 more
core   +4 more sources

Signal Integration in Plant Abiotic Stress Responses via Multistep Phosphorelay Signaling

Frontiers in Plant Science, 2021
Plants growing in any particular geographical location are exposed to variable and diverse environmental conditions throughout their lifespan. The multifactorial environmental pressure resulted into evolution of plant adaptation and survival strategies ...
Jan Skalak, Katrina Leslie Nicolas, Radomira Vankova, Jan Hejatko   +3 more
doaj   +1 more source

Light perception and signalling by phytochrome A [PDF]

Journal of Experimental Botany, 2013
In etiolated seedlings, phytochrome A (phyA) mediates very-low-fluence responses (VLFRs), which initiate de-etiolation at the interphase between the soil and above-ground environments, and high-irradiance responses (HIR), which complete de-etiolation under dense canopies and require more sustained activation with far-red light.
Casal, Jorge Jose, Candia, A. N., Sellaro, Romina Vanesa   +2 more
openaire   +3 more sources

Studies on Structure and Dynamics of Components of Phytochrome Mediated Light Signaling in Plants and Cyanobacteria [PDF]

, 2003
From a structural point of view, phytochrome mediated light signaling in plants and bacteria constitutes a scarcely understood system. Albeit the tremendous research activity in the field, no X-ray or NMR-based structural information is available.
Benda, Christian G.
core   +1 more source