Results 101 to 110 of about 856,839 (311)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Light-induced states in the transient-absorption spectrum of a periodically pumped strong-field-excited system

open access: yes, 2018
The transient-absorption spectrum of a $V$-type three-level system is investigated, when this is periodically excited by a train of equally spaced, $\delta$-like pump pulses as, e.g., from an optical-frequency-comb laser.
Juliane Haug (17495541)   +1 more
core   +1 more source

Vertical Production of ‘Konstancin’ Rose Cuttings in the Growth Chamber Under Led Light

open access: yesJournal of Horticultural Research, 2020
The impact of light quality generated by light-emitting diodes (LEDs) on the adventitious root formation and cuttings’ quality of rose hip ‘Konstancin’ under controlled conditions in multilevel growth chamber without access to natural light and in the ...
Matysiak Bożena
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Spectrum and wave functions of excited states in lattice gauge theory

open access: yes, 2008
We suggest a new method to compute the spectrum and wave functions of excited states. We construct a stochastic basis of Bargmann link states, drawn from a physical probability density distribution and compute transition amplitudes between stochastic ...
Hosseinizadeh, Ahmad   +3 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Excited light meson spectroscopy from lattice QCD [PDF]

open access: yes, 2012
I report on recent progress in calculating excited meson spectra using lattice QCD, emphasizing results and phenomenology. With novel techniques we can now extract extensive spectra of excited mesons with high statistical precision, including spin-four ...
Christopher Thomas, Hadron Spectrum Collaboration
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

An earthquake response spectrum method for linear light secondary substructures

open access: yes, 2007
YesEarthquake response spectrum is the most popular tool in the seismic analysis and design of structures. In the case of combined primary-secondary (P-S) systems, the response of the supporting P substructure is generally evaluated without considering ...
Palmeri, Alessandro, Muscolino, G.
core  

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