Results 41 to 50 of about 342,618 (242)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Regularized topology optimization for light trapping structure in solar cells
Frontiers in NanotechnologyEfficient light trapping bulk structures can significantly enhance light absorption in solar cells while reducing manufacturing costs. However, locating the optimal set of design parameters within a complex solution space remains challenging.
Zijian Zhang
doaj +1 more source
Scientific Reports, 2019 It is important to develop solar cells that can capture and utilize omnidirectional light in urban environments, where photovoltaic (PV) devices are installed in fixed directions.
Min Ju Yun +3 more
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Beauty is Attractive: Moduli Trapping at Enhanced Symmetry Points [PDF]
, 2004 We study quantum effects on moduli dynamics arising from the production of particles which are light at special points in moduli space. The resulting forces trap the moduli at these points, which often exhibit enhanced symmetry. Moduli trapping occurs in
A. Linde +44 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Eliminating light shifts for single atom trapping
New Journal of Physics, 2017 Microscopically controlled neutral atoms in optical tweezers and lattices have led to exciting advances in the study of quantum information and quantum many-body systems.
Nicholas R Hutzler +3 more
doaj +1 more source
Nanomaterials, 2022 Surface anti-reflection (AR) with nanometer-scaled texture has shown excellent light trapping performance involving optical devices. In this work, we developed a simple and lithography-free structure replication process to obtain large scale surface cup ...
Tangyou Sun +9 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Trapping of light with angular orbital momentum above the light cone
Advanced Electromagnetics, 2017 We consider bound states in the radiation continuum (BSC) above the light cone in an one-dimensional periodic array of dielectric spheres in air. The BSCs are classified by orbital angular momentum m, Bloch wave vector β directed along the array, and ...
E. Bulgakov, A. Sadreev
doaj +1 more source