Results 131 to 140 of about 783,623 (305)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Effects of Light Quality and Photoperiod on Growth, Dry Matter Production and Yield of Ginger

Plants
We investigated the effects of light quality and photoperiod on the phenotypic characteristics, dry matter production, and yield of ginger under three light quality ratios (A1: blue light: white light = 1:4; A2: blue light: white light = 1:1; A3: pure ...
Haodan Zhang, Xingyue Li, Tao Han, Qin Huang, Junlan Liu, Ailin Tian, Linyu Liu, Guoqing Sun, Ling Dong, Hanyu Wang, Xintong Xie, Siyu Peng, Qiang Li, Honglei Li   +13 more
doaj   +1 more source

Light Yield Response of Neutron Scintillation Screens to Sudden Flux Changes. [PDF]

J Imaging, 2020
Neuwirth T, Walfort B, Sebold S, Schulz M.   +3 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A comparative study on the scintillation characteristics of Gd2SiO5:Ce and Lu1.2Gd0.8SiO5:Ce scintillators

Materials Research Express
In the present day, inorganic scintillators have been developed to detect high-energy photons such as x-rays and γ -rays. They have been applied in many works, such as astronomy, materials inspection, high energy physics, industrial application, and ...
Akapong Phunpueok, Sarawut Jaiyen, Tossawat Autila, Voranuch Thongpool   +3 more
doaj   +1 more source

Effects of Plant Density and Row Spacing on Canopy Structure, Light Use Efficiency, and Yield of Drip-Irrigated Soybean

Agriculture
Increasing planting density is a common strategy to raise soybean yield, yet it often intensifies light competition within the canopy, leading to diminishing returns at high densities. Optimizing row spacing to improve canopy light distribution and light
Kangxu Zhang, Mengjiao Li, Huifang Wang, Jianguo Liu   +3 more
doaj   +1 more source

Measuring Thickness-Dependent Relative Light Yield and Detection Efficiency of Scintillator Screens. [PDF]

J Imaging, 2020
Chuirazzi WC, Craft AE.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Separate and Combined Effects of Supplemental CO₂, Gibberellic Acid, and Light on Hop Quality and Yield

Plants
We investigated the effect of supplemental CO2, gibberellic acid (GA3), and light on the quality and yield of Humulus lupulus L. strobili (cones).
William L. Bauerle
doaj   +1 more source