Results 131 to 140 of about 5,756,769 (295)
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Measuring Thickness-Dependent Relative Light Yield and Detection Efficiency of Scintillator Screens. [PDF]
J Imaging, 2020 Chuirazzi WC, Craft AE.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Yield trends and yield gap analysis of major crops in the world [PDF]
, 2009 This study aims to quantify the gap between current and potential yields of major crops in the world, and the production constraints that contribute to this yield gap. Using an expert-based evaluation of yield gaps and the literature, global and regional
Hengsdijk, H., Langeveld, J.W.A.
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
STRUCTURAL MODELS OF AREA YIELD CROP INSURANCE [PDF]
Earlier analyses of area yield crop insurance schemes used a reduced form linear relationship between individual and area yield. However, without knowledge of the structural framework, the analysis and design of alternative schemes is problematic.
Ramaswami, Bharat, Roe, Terry L.
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Materials Research ExpressIn the present day, inorganic scintillators have been developed to detect high-energy photons such as x-rays and γ -rays. They have been applied in many works, such as astronomy, materials inspection, high energy physics, industrial application, and ...
Akapong Phunpueok +3 more
doaj +1 more source
Eurasian Journal of Physics and Functional MaterialsAn intense high-temperature thermally stimulated luminescence (TSL) dosimetric peak at 505 K was discovered in KCl:Li crystals. At a lithium concentration of 400 ppm, its integral light yield (ηKCl:Li) associated with the TSL505К peak exceeds the ...
Shynar Sagimbayeva +3 more
doaj +1 more source