Results 141 to 150 of about 5,756,769 (295)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Is Area Yield Insurance Competitive with Farm Yield Insurance? [PDF]

open access: yes
This article compares risk reduction from MPCI and GRP crop insurance contracts. The analysis extends and improves on the existing area-yield insurance literature in four important respects.
Skees, Jerry R.   +3 more
core  

Light yield of NE-102A irradiated by low energy heavy ions (- 160 MeV).

open access: yes, 2018
Light yield of NE-102A irradiated by low energy heavy ions (- 160 MeV).
Tatsuhiko Ogawa (3846838)   +2 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Effects of Plant Density and Row Spacing on Canopy Structure, Light Use Efficiency, and Yield of Drip-Irrigated Soybean

open access: yesAgriculture
Increasing planting density is a common strategy to raise soybean yield, yet it often intensifies light competition within the canopy, leading to diminishing returns at high densities. Optimizing row spacing to improve canopy light distribution and light
Kangxu Zhang   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Yield Curve Dynamics: Regional Common Factor Model [PDF]

open access: yes
In this paper, we focus on thorough yield curve modelling. We build on extended classical Nelson-Siegel model, which we further develop to accommodate unobserved regional common factors.
Boril Šopov, Jakub Seidler
core  

Maximizing Energy Yield: The Optimal Tilt Angle and Orientation in Agrivoltaic Systems with Light Productivity Factor

open access: yes
The combined agriculture and photovoltaic system are a trade-off between the amount of light received by the solar panel and the percentage of the light reaching the ground level.
Deilami, S, Natasha, AT, Taghizadeh, F
core   +1 more source

Analysis of growth dynamics of Mediterranean bioenergy crops [PDF]

open access: yes, 2011
In spite of the rapidly growing bioenergy production worldwide, there is lack of field experience and experimental data on the cultivation of bioenergy crops.
Archontoulis, S.V.
core  

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