Results 51 to 60 of about 3,193,855 (298)
Individual control of electric lighting in a daylit space
, 2008 Participants (N=40) occupied a glare-free, daylit office laboratory for one day, and were prompted every 30 minutes to use dimming control over electric lighting to choose their preferred light level.
Newsham, GR +14 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Megaron, 2017 This paper presents the results of a 2-phase study conducted in order to understand the current state of lighting design education in interior design departments in Turkey and Northern Cyprus, and to report whether or not there is a need to adopt a ...
Sezin Hatice Tanrıöver +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
International Archives of Health Sciences, 2016 Aims: Work proper lighting means a safe, healthy and comfort conditions for work under a lighting system that includes qualitative and quantitative features.
A.R. Mashkoori +5 more
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
A Reassessment of General Lighting Practice Based on the MRSE Concept
Journal of Sustainable Design and Applied Research in Innovative Engineering of the Built Environment, 2016 A case is made for reassessment of the purpose of general lighting practice, involving a change from lighting standards specifying illuminance for high levels of visual performance, to providing for predictable assessments of surrounding brightness. Mean
Christopher Cuttle
doaj +1 more source
Studying The Evolution of Lighting units Techniques in Islamic Art
Journal of Architecture, Art & Humanistic Science, 2020 Lighting is one of the main pillars of life, and since the sun is the main source of natural lighting that can not live without human, industrial lighting was also one of the inventions that have become one of the most important elements of life, where ...
Mona Gabr +2 more
doaj +1 more source