Results 41 to 50 of about 321,608 (299)

Continual Learning for Multimodal Data Fusion of a Soft Gripper

Advanced Robotics Research, EarlyView.
Models trained on a single data modality often struggle to generalize when exposed to a different modality. This work introduces a continual learning algorithm capable of incrementally learning different data modalities by leveraging both class‐incremental and domain‐incremental learning scenarios in an artificial environment where labeled data is ...
Nilay Kushawaha, Egidio Falotico
wiley   +1 more source

Spatiotemporal Characteristics of Development Speed of Downward Positive Cloud-to-ground Lightning Leader Channels in Guangzhou

应用气象学报
Positive cloud-to-ground (CG) natural lightning typically exhibits higher energy release than negative CG lightning, with greater peak current, longer duration, and larger charge transfer.
Shao Xinran, Wu Bin, Lü Weitao, Qi Qi, Lü Fanchao, Ma Ying, Chen Lüwen, Liu Hengyi, Xu Weiqun   +8 more
doaj   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

A Simplified Top-Oil Temperature Model for Transformers Based on the Pathway of Energy Transfer Concept and the Thermal-Electrical Analogy

Energies, 2017
This paper presents an alternative approach to determine the simplified top-oil temperature (TOT) based on the pathway of energy transfer and thermal-electrical analogy concepts.
Muhammad Hakirin Roslan, Norhafiz Azis, Mohd Zainal Abidin Ab Kadir, Jasronita Jasni, Zulkifli Ibrahim, Azalan Ahmad   +5 more
doaj   +1 more source

Estimation of Lightning Activity of Squall Lines by Different Lightning Parameterization Schemes in the Weather Research and Forecasting Model

Remote Sensing, 2023
Based on three-dimensional lightning data and an S-band Doppler radar, a strong relationship was identified between lightning activity and the radar volume of squall lines. A detailed analysis of the squall line investigates the relationship following an
Dongxia Liu, Han Yu, Chunfa Sun
doaj   +1 more source

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Advances of Observation and Study on Tall-object Lightning in Guangzhou over the Last Decade

应用气象学报, 2020
Comparing to the ground or low-object, tall-object is more likely to reach the threshold for the initiation of leader on its top due to the distortion and enhancement of electric field, therefore tall-object is not only easier to get struck by downward ...
Lü Weitao, Chen Lüwen, Ma Ying, Qi Qi, Wu Bin, Jiang Ruijiao   +5 more
doaj   +1 more source

Luminosity and Current Characteristics of Metal-vaporized Channel of an Artificially Triggered Lightning

应用气象学报, 2023
Channel current is an important parameter of the lightning discharge, but it's difficult to be directly measured due to the randomness and instantaneity of the natural lightning. The channel luminosity, however, is relatively easier to obtain.
Xu Weiqun, Lü Weitao, Qi Qi, Fan Yanfeng, Chen Lüwen, Wu Bin, Wang Xuejuan, Ma Ying, Xia Dengcheng   +8 more
doaj   +1 more source