Results 61 to 70 of about 98,805 (251)

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source

Hippocampal Seizure‐Related Burden is Associated with Accelerated Long‐Term Forgetting in Focal Epilepsy

Annals of Neurology, EarlyView.
Objective Memory impairment is a frequent comorbidity of focal epilepsy, incompletely explained by seizure frequency or structural pathology. Ictal and postictal hippocampal dysfunction disrupt memory processes, but their cumulative impact remains poorly quantified.
Ionuț‐Flavius Bratu, Isabelle Lambert, Olivier Felician, Samuel Medina Villalon, Agnès Trébuchon, Fabrice Bartolomei   +5 more
wiley   +1 more source

Effects of Lightning Impulses on the Dielectric Properties of HDPE

, 2009
Impulse over-voltages are very common phenomena in electric power systems. Switching impulses are created by switching surges or local faults while lightning impulses are due to lightning strikes to overhead lines.
Dao, N L, Swingler, S G, Lewin, P L
core   +1 more source

Effects of oropharyngeal neuromuscular stimulation on the volumetric enlarged and reduced tongue base in minipigs

The Anatomical Record, EarlyView.
Abstract Hypoglossal nerve or tongue protruding muscle stimulation is a current treatment option for obstructive sleep apnea. Thus, the present study analyzed 3D deformations of the volumetric enlarged and reduced tongue base upon oropharyngeal neuromuscular stimulation.
Sydney Chen, Doris Haydee Rosero Salazar, Zi‐Jun Liu   +2 more
wiley   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Optimizing Grid With Dynamic Line Rating of Conductors: A Comprehensive Review

IEEE Access
As the world is pledged towards net zero carbon by 2050, the need for clean and efficient energy transitions is more critical than ever. Optimizing the power grid transfer capacity is crucial for maintaining grid stability and reliability.
Nurul Husniyah Abas, Mohd Zainal Abidin Ab Kadir, Norhafiz Azis, Jasronita Jasni, Nur Fadilah Ab Aziz, Zmnako Mohammed Khurshid   +5 more
doaj   +1 more source

The Rich Chemistry of Ionized Methanol With Sulfur Dioxide: Pathways to Prebiotic and Elusive Species in Earth's Atmosphere and Space

Chemistry – A European Journal, EarlyView.
The reaction between the methanol radical cation and sulfur dioxide is remarkably fast and forms several ionic and neutral products (HOSOH+, CH2OSO+, CH2OH+, CH2O, H2O, HSO2). The chemistry goes beyond simple proton or hydrogen transfer, revealing a close interaction between the two species, relevant to atmospheric and astrochemical environments where ...
Mauro Satta, Daniele Catone, Mattea Carmen Castrovilli, Antonella Cartoni   +3 more
wiley   +1 more source

Bond Formation: Shaken, Not Stirred

Chemistry – A European Journal, EarlyView.
Shaking of seismo‐molecules efficiently transforms kinetic energy into storable chemical potential, unlocking high‐utility Gibbs free energy. This innovative mechanism pioneers uncharted scientific frontiers, introducing fascinating phenomena like seismochemistry, seismochromism, and seismofluorescence that redefine the boundaries of molecular ...
Alexander D. Q. Li
wiley   +1 more source

Attachment of lightning flashes to grounded structures

, 2012
A grounded structure can interact with a lightning flash in two different ways. It can interact with either a downward or an upward lightning flash. The initiation of a downward lightning flash takes place in the cloud, whereas in the case of upward ...
Cooray, Vernon,, Vernon Cooray
core   +1 more source

Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays

Cytoskeleton, EarlyView.
ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz, Benjamin Powers, Jayne Aiken   +2 more
wiley   +1 more source