Results 71 to 80 of about 150,904 (350)

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

Study on lightning strike risk of ship based on lightning leader fractal model

Zhongguo Jianchuan Yanjiu, 2023
ObjectiveIn order to set or improve the lightning protection measures of ships, it is necessary to evaluate the strike risk of critical equipment and the protection effect of the lightning rod.MethodsIn this paper, a lightning leader fractal model is ...
Xudong ZHANG, Jiajun LU, Ziying YU, Bangyong WANG, Bin CAO, Jun GUO, Yanzhao XIE   +6 more
doaj   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

Lightning-Discharge [PDF]

Science, 1890
n ...
openaire   +6 more sources

Differences in Optical Two-dimensional Morphological Characteristics of Downward Lightning Channels with Different Polarities

应用气象学报
Proportions of positive and negative cloud-to-ground (CG) natural lightning are approximately 10% and 90%, respectively. Although the frequency of positive CG lightning is relatively low, these events are more likely to produce high current peaks ...
Mei Ji, Lü Weitao, Qi Qi, Xu Weiqun, Wu Bin, Ma Ying, Liu Hengyi, Chen Lüwen, Zhang Yang   +8 more
doaj   +1 more source

Advances of Observation and Study on Tall-object Lightning in Guangzhou over the Last Decade

应用气象学报, 2020
Comparing to the ground or low-object, tall-object is more likely to reach the threshold for the initiation of leader on its top due to the distortion and enhancement of electric field, therefore tall-object is not only easier to get struck by downward ...
Lü Weitao, Chen Lüwen, Ma Ying, Qi Qi, Wu Bin, Jiang Ruijiao   +5 more
doaj   +1 more source

Formation of Saturn's ring spokes by lightning-induced electron beams

, 2006
Spokes are near-linear markings sometimes visible on Saturn's rings. They are widely accepted as being electrostatically-levitated sheets of similar to 0.6 micron-radius charged grains.
Lagg, A, Roussos, E, Mitchell, DG, Krüger, H., Jones, G., Arridge, C., McAndrews, HJ, Krupp, N., Krupp, N, Dougherty, MK, Jones, G. H., Woch, J, Arridge, C. S., Krimigis, S., Kruger, H, Ip, WH, Franz, M, Mitchell, D., Woch, J., Ip, W., McAndrews, H. J., McAndrews, H., Mitchell, D. G., Krimigis, S. M., Arridge, CS, Lagg, A., Fränz, M., Dougherty, M. K., Dougherty, M., Ip, W.-H., Jones, GH, Krimigis, SM, Roussos, E.   +32 more
core   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

High-speed Video Observations on Abrupt Elongations of the Positive End of Bidirectional Leader

应用气象学报, 2020
One of the most important advances in lightning physics research in recent decades is the introduction of the the bidirectional developmengt of leaders and its observation and verification, but this theory is not paid much attention until more and more ...
Wu Bin, Lü Weitao, Qi Qi, Ma Ying, Chen Lüwen, Jiang Ruijiao   +5 more
doaj   +1 more source

Lightning-caused fires in the Alps: Identifying the igniting strokes

Agricultural and Forest Meteorology, 2020
Lightning is the most important natural wildfire ignition source worldwide. However, identifying the specific lightning causing a forest fire is a challenging task.
J. Moris, M. Conedera, Luca Nisi, M. Bernardi, G. Cesti, G. Pezzatti   +5 more
semanticscholar   +1 more source