Results 191 to 200 of about 75,865 (305)

New Insights Into Changes in the DNA Methylation Pattern of the SHOX Gene in Patients With Léri‐Weill Dyschondrosteosis

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 606-618, March 2026.
ABSTRACT SHOX gene haploinsufficiency is associated with Léri‐Weill dyschondrosteosis (LWD) or idiopathic short stature (ISS) and could be caused by the structural and point mutations in the coding region and by the deletions in SHOX gene regulatory sequences. The role of the duplications in regulatory sequences is ambivalent.
Valeriia Kopytko   +3 more
wiley   +1 more source

Chronic cerebral hypoperfusion exacerbates amyloid and tau pathology by impairing glymphatic transport via AQP4‐ and VEGF‐mediated pathways: insights from a vascular to mixed‐type dementia model

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Chronic cerebral hypoperfusion (CCH) is a major contributor to cognitive impairment; however, its underlying mechanisms remain poorly understood. METHODS We investigated CCH‐induced glymphatic dysfunction and neurodegeneration in amyloid precursor protein (APP)/presenilin 1 (PS1) and wild‐type mice.
Jia‐Hung Chen   +8 more
wiley   +1 more source

Time‐Domain Geoelectrical Modeling and Experimental Validation of Ground Potential Rise in Multilayer Soil Structures during Fault Events

open access: yesEnergy Science &Engineering, Volume 14, Issue 3, Page 1492-1504, March 2026.
This study develops a time‐domain geoelectrical model of ground potential rise (GPR) in multilayer soil that couples electromagnetic field theory with nonlinear fault arc resistance. Finite‐element simulations calibrated against scaled fault‐injection experiments reproduce measured GPR and step/touch voltages within 4.7% error, revealing that steady ...
Wulfran Fendzi Mbasso   +7 more
wiley   +1 more source

Wild‐Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 2, Page 162-171, March 2026.
ABSTRACT Exposure to altered nighttime lighting conditions has become common in today's modern world. Light at night disrupts circadian processes that govern feeding patterns, sleep/wake cycles, and metabolic homoeostasis, increasing the risk of developing pathologies associated with cardiometabolic disease. Yet, the underlying mechanism(s) responsible
Kevin Pham   +4 more
wiley   +1 more source

Hell's Itch: An Acute Reaction to Sunburn Exposure

open access: yesJEADV Clinical Practice, Volume 5, Issue 1, Page 234-236, March 2026.
ABSTRACT Hell's itch is a neurocutaneous dysesthesia following sunburn that is underreported in scientific literature despite considerable discussion online. ‘Hell's itch’ describes an acute, uncontrollable itch with intense stabbing pain several days post‐sunburn and often follows an inciting event such as water exposure.
Colin Kelly   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy