Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima +11 more
wiley +1 more source
The two-step purification method ViREn identifies a single NSUN6-mediated 5-methylcytosine modification promoting dengue virus RNA genome turnover. [PDF]
Wu CC +19 more
europepmc +1 more source
Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells
Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari +6 more
wiley +1 more source
The Stuck Electorate: Polarization, Nationalization, and the Consolidation of Party in the Trump Era
ABSTRACT The 2024 presidential election unfolded under extraordinary circumstances—the mid‐campaign withdrawal of an incumbent president, the nomination of the first woman of color by a major party, and the reelection of a president defeated 4 years earlier. Yet the outcome revealed an electorate that looked much like 2016 and 2020.
Jamie L. Carson, Stewart Ulrich
wiley +1 more source
Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite
This study characterized clathrin function in hemoglobin uptake from host red blood cells via the malaria parasite's specific endocytosis machinery, cytostome. Clathrin heavy chain, clathrin light chain, and AP‐1 γ subunit were found associated with certain proteins known to be involved in cytostome function, and they were localized at the collars of ...
Jun Miao +10 more
wiley +1 more source
Hyperspectral imaging and its applications: A review. [PDF]
Bhargava A +5 more
europepmc +1 more source
Observations of lightning in relation to transitions in volcanic activity during the 3 June 2018 Fuego Eruption. [PDF]
Schultz CJ +3 more
europepmc +1 more source
Chromosomal Aberration t(14;17)(q32;q21) Simultaneously Activates HOXB5 and miR10a in Triple-Hit B-Cell Lymphoma. [PDF]
Nagel S +4 more
europepmc +1 more source
Abstract Extensive research in humans, dogs, rabbits, rats, mice and other mammals has consistently demonstrated that coronary blood flow (CBF) peaks during ventricular diastole. For example, studies using transthoracic Doppler echocardiography in anaesthetized rats and mice, isolated blood‐perfused rat hearts and Doppler probes sutured to the ...
Heidi L. Lujan +2 more
wiley +1 more source
Near-Surface Air Temperature Estimation Based on an Improved Conditional Generative Adversarial Network. [PDF]
Zheng J, Wu X, Li X, Peng J.
europepmc +1 more source

