Results 81 to 90 of about 16,927 (196)

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6606-6616, 30 August 2026.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim, Rixing Cong, Jin‐Soo Park, Keunwan Park, Kyungsu Kang, Soon‐Mi Shim   +5 more
wiley   +1 more source

Cecal microbiota and mammary gland microRNA signatures are related and modifiable by dietary flaxseed with implications for breast cancer risk

Microbiology Spectrum
The gut microbial ecosystem underlies physiological relationships between the gut and distal organs. Mechanisms remain elusive but rely at least partially on the production of a diverse set of absorbable metabolites and host gene expression regulation ...
Diana Wu, Lilian U. Thompson, Elena M. Comelli   +2 more
doaj   +1 more source

HetCA/STOCSY‐Guided Dereplication of Artemisia arborescens Reveals Furofuran Lignans with Antileishmanial Effects

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Bioactive metabolites can remain hidden in negligible activity extracts. A statistical spectroscopy–driven dereplication workflow integrating the HeteroCovariance Approach (HetCA) and Statistical Total Correlation Spectroscopy (STOCSY) prioritized furofuran lignans in Artemisia arborescens, identifying three compounds with moderate antileishmanial ...
Olga Karoutzou, Stavros Beteinakis, Olga Koutsoni, Despina Smirlis, Maria Halabalaki, Leandros Alexios Skaltsounis, Emmanuel Mikros   +6 more
wiley   +1 more source

Determination of secoisolariciresinol diglucoside by high performance liquid chromatography

浙江大学学报. 农业与生命科学版, 2008
High performance liquid chromatography-photodiode array detection-elctrospray ionizationmass spectrometry (HPLC-PAD-ESI-MS) method was used to determine secoisolariciresinol diglucoside (SDG) qualitatively and quantitatively. Precision, stability, limits
ZHANG Wen-bin, XU Shi-ying, WANG Zhang, YANG Rui-jin, LU Rong-rong   +4 more
doaj   +1 more source

The One‐Step Synthesis of Biologically Active Isochromans from Lignin‐Derived Aromatic Monomers in Tunable Deep Eutectic Solvents

Chemistry – A European Journal, Volume 32, Issue 30, 13 August 2026.
A straightforward one‐step protocol enables the synthesis of bio‐based and biologically active isochromans through the Oxa‐Pictet cyclization involving diverse aldehydes, including vanillin in combination with lignin‐derivable homovanillyl alcohol, a prominent aromatic platform chemical obtainable via diol‐assisted fractionation of lignocellulose ...
Anjali Kottayi, Anastasiia M. Afanasenko, Antonio A. Castillo‐Garcia, Walid A. M. Elgaher, Jörg Haupenthal, Anna K. H. Hirsch, Katalin Barta   +6 more
wiley   +1 more source

Pinus pinea L. Periderm as a Sustainable Source of Phenolic Bioactives: Integrated Phytochemical, Antioxidant, and Elemental Investigation

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
A hydroalcoholic extract from the renewable periderm of Pinus pinea is characterized through integrated phytochemical, biological and elemental analyses. The extract exhibits a phenolic‐rich composition, significant antioxidant activity and preliminary protection against oxidative stress in SH‐SY5Y cells, while elemental profiling indicates low levels ...
Vlad Sebastian Popescu, Fabjola Bilo, Eileen Mac Sweneey, Laura Borgese, Gregorio Peron, Giulia Abate, Andrea Mastinu   +6 more
wiley   +1 more source

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

eFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang, Ling Wei, Kaibing Zhou, Qin Deng, Muhammad Mobeen Tahir, Hongxia Wu, Minjie Qian   +6 more
wiley   +1 more source

Interaction Among Microbiota, Chemical Composition, and Quality Variations in Coffea arabica Across Altitudinal Gradients During Wet Processing

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Fermentation significantly altered the dominant bacterial genera from Sphingomonas and Pleomorphomonas (before fermentation) to Weissella and Lactobacillus (after fermentation), while Cladosporium and Fusarium remained the dominant fungal genera. Notably, non‐volatile compounds in de‐pulping coffee beans and volatile compounds of roasted coffee beans ...
Xiaojing Shen, Yamei Wu, Qi Wang, Wenhua Chen, Bintao Peng, Surui Lu, Ying Yang, Kunyi Liu, Jilai Zhang   +8 more
wiley   +1 more source

Gastroprotective Effects of Nettle‐ and Carob‐Enriched Snail Mucus in a Rat Model of Gastric Injury: Role of Antioxidant and Anti‐Inflammatory Mechanisms

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Dietary enrichment of Helix aspersa mucus with Urtica dioica or Ceratonia siliqua extracts increased its phenolic, flavonoid, protein, and glycoprotein content in a dose‐dependent manner, with nettle showing the strongest effect. In an ethanol‐induced rat model of gastric ulcer, the 30% nettle‐enriched mucus (SSUD30%) markedly reduced gastric lesions ...
Khaoula Gharbi, Slimen Selmi, Soumaya Wahabi, Hanen Kahlaoui, Karima Tlili, Stefano D'allacqua, Hichem Sebai   +6 more
wiley   +1 more source

Phillyrin Alleviates Memory Impairment in D‐Galactose‐Induced Aged Mice by Suppressing Hippocampal Neuroinflammation via the TLR4/NF‐κB Signaling Pathway

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Phillyrin (PHI), a dietary bioactive lignan isolated from Forsythia suspensa, alleviates D‐galactose‐induced cognitive impairment by suppressing the TLR4/NF‐κB signaling pathway. PHI inhibits TLR4‐mediated activation of NF‐κB, thereby reducing neuroinflammation and oxidative stress, preserving neuronal structure and synaptic plasticity, and ultimately ...
Xuemin Li, Liru Wang, Chenyang Li, Junfeng Huo, Shuqin Li, Linxiu Bian, Ying Zhang, Yongfei Bai, Jie Yao, Xinyuan Hao   +9 more
wiley   +1 more source