Results 71 to 80 of about 27,833 (238)

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim, Rixing Cong, Jin‐Soo Park, Keunwan Park, Kyungsu Kang, Soon‐Mi Shim   +5 more
wiley   +1 more source

Bioactive phenols in leaves of Forsythia species

International Journal of Horticultural Science, 2008
Nowadays a number of lignans (arctigenin, matairesinol, pinoresinol and phillygenin) have come to the fore in research due to their various biological activities.
É. Sedlák, L. Borsodi, E. Boldizsár, É. Preininger, M. László, É. Szőke, I. Gyurján   +6 more
doaj   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

A New Tetrahydrofuran Lignan Diglycoside from Viola tianshanica Maxim

Molecules, 2013
A new lignan glycoside, tianshanoside A (1), together with a known phenylpropanoid glycoside, syringin (2) and two known lignan glycosides, picraquassioside C (3), and aketrilignoside B (4), were isolated from the whole plant of Viola tianshanica Maxim ...
Yan Qin, Chengle Yin, Zhihong Cheng
doaj   +1 more source

Higher usual dietary intake of phytoestrogens is associated with lower aortic stiffness in postmenopausal women [PDF]

, 2002
Objective¿ Phytoestrogens have been postulated to protect against cardiovascular diseases, but few studies have focused on the effect of Western dietary phytoestrogen intake.
Bots, M.L., Grobbee, D.E., Lamberts, S.W.J., Lebrun, C.E.I., Peeters, P.H.M., Pijpe, A., Schouw, Y.T., van der, Staveren, W.A., van   +7 more
core   +3 more sources

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Honokiol: An anticancer lignan

Biomedicine & Pharmacotherapy, 2018
Honokiol ((3',5-di-(2-propenyl)-1,1'-biphenyl-2,2'-diol), a lignan, is a promising antitumor compound, having exerted activity against a number of human cancer cell lines. Honokiol has inhibitory role on the proliferation, invasion and survival of cancer cells in in vitro as well as in vivo studies.
Abdur Rauf, Seema Patel, Muhammad Imran, Aneela Maalik, Muhammad Umair Arshad, Farhan Saeed, Yahia N. Mabkhot, Salim S. Al-Showiman, Nazir Ahmad, Eman Elsharkawy   +9 more
openaire   +2 more sources

Lignans in Flaxseed [PDF]

Czech Journal of Food Sciences, 2009
Lignans are phytoestrogens which are present in a wide variety of plants. Epidemiological studies indicate that phytoestrogen-rich diets reduce risk of various hormone-dependent cancers, heart disease, and osteroporosis. One of the reachest dietary sources of lignans are flaxseeds, with glycosides of secoisolariciresinol (SECO) and matairesinol (MAT ...
A. Krajčová, V. Schulzová, J. Hajšlová, M. Bjelková   +3 more
openaire   +2 more sources

Pedicularis L. Genus. Systematics, botany, phytochemistry, chemotaxonomy, ethnopharmacology, and other [PDF]

, 2019
In this review, the relevance of the plant species belonging to the Pedicularis L. genus has been considered from different points of view. Particular emphasis was given to phytochemistry and ethnopharmacology, since several classes of natural compounds ...
Bianco, Armandodoriano, Ciccòla, Alessandro, De Vita, Daniela, Foddai, Sebastiano, Franceschin, Marco, Frezza, Claudio, Guiso, Marcella, Nicoletti, Marcello, Serafini, Ilaria, Serafini, Mauro, Tomassini, Lamberto, Toniolo, Chiara, Venditti, Alessandro, Ventrone, Antonio   +13 more
core   +1 more source

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

Phytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source