Results 11 to 20 of about 17,805 (207)
Molecules, 2019 The 13 research articles/communications, six reviews, and one perspective that comprise this Special Issue on Lignans, highlight the most recent research and investigations into this diverse and important class of bioactive natural products [...]
David Barker
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Importance of interaction between the matrix effect and microbial metabolism in the bioavailability of lignans. [PDF]
J Sci Food AgricAbstract BACKGROUND Plant‐lignans are polyphenols with low bioavailability and bioactivity that are transformed by the intestinal microbiota into enterolignans. Our hypotheses are: (i) the way in which plant‐lignans are ingested in the diet affects, in a decisive way, the microbial metabolism of these compounds and (ii) an increase in lignan ...
Langa S +4 more
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Lignans: a versatile source of anticancer drugs
Beni-Suef University Journal of Basic and Applied Sciences, 2022 Background Cancer is considered as the second deadliest disease globally. Plants have continuously offered unique secondary metabolites with remarkable biological applications.
Minky Mukhija +4 more
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Cosmetics, 2018 A number of approaches can be implemented to ensure plant-based material authentication for cosmetic applications. Doing this requires knowledge and data dealing with botany, molecular biology, and analytical chemistry, the main techniques of which are ...
Samantha Drouet +7 more
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New Phenolics from Linum mucronatum subsp. orientale [PDF]
BioImpacts, 2014 Introduction: Lignans and flavonoids are widely distributed phenolics in the plant kingdom. Aryltetralin type lignans (podophyllotoxin derivatives) as the major secondary metabolites of Linum species play an important role in the production of ...
Khadijeh Zare +4 more
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Arylnaphthalene lignans with a focus Linum species: a review on phytochemical, biotechnological and pharmacological potential [PDF]
PharmaciaLignans are a large group of dimeric phenylpropanoids with a long and distinguished history of medicinal use in the ancient cultures of many peoples. The two main groups, -aryltetralin and arylnaphthalene lignans, are leading compounds with important ...
Rada Nedelcheva +5 more
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Advances in the roles and mechanisms of lignans against Alzheimer’s disease
Frontiers in Pharmacology, 2022 Background: Alzheimer’s disease (AD) is a serious neurodegenerative disease associated with the memory and cognitive impairment. The occurrence of AD is due to the accumulation of amyloid β-protein (Aβ) plaques and neurofibrillary tangles (NFTs) in the ...
Na Han +5 more
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Cellular Physiology and Biochemistry, 2016 Background/Aims: Advanced glycation end products (AGEs) could elicit oxidative stress, trigger and aggravate endothelium damage in several ischemic retinopathies including diabetic retinopathy (DR). The leaves of Eucommia ulmoides O., also referred to as
Ban Liu +4 more
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Oxidative Transformations of Lignans [PDF]
Molecules, 2019 Numerous oxidative transformations of lignan structures have been reported in the literature. In this paper we present an overview on the current findings in the field. The focus is put on transformations targeting a specific structure, a specific reaction, or an interconversion of the lignan skeleton. Oxidative transformations related to biosynthesis,
Patrik A. Runeberg +3 more
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NMR Characterization of Lignans
Molecules, 2022 Lignans are particularly interesting secondary metabolites belonging to the phenyl-propanoid biosynthetic pathway. From the structural point of view, these molecules could belong to the aryltetralin, arylnaphtalene, or dibenzylbutyrolactone molecular skeleton.
Consonni R, Ottolina G
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