Results 61 to 70 of about 26,355 (196)

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

The untargeted metabolomic analysis of Ammodaucus leucotrichus Coss. & Dur. seeds reveals previously undescribed polar lignans and terpenoids [PDF]

The polar metabolome of the medicinal plant Ammodaucus leucotrichus Coss. & Dur. has not been comprehensively characterised. In this study, the chemical composition of a water/methanol (4:1) extract of seeds was determined through a combination of UHPLC ...
Noleto-Dias, C., Sobeh, M., Naboulsi, I., Bitchagno-Mbahbou, G., Kisiriko, M., Anastasiadi, M., Beale, M. H., Terry, L. A., Ward, J. L.   +8 more
core   +1 more source

HPLC-MS/MS triple quadrupole method to quantify lignans in espresso coffee.

, 2017
Lignans are a group of polyphenolic compounds that are considered phytoestrogens due to their plant origins as well as their anti-estrogenic and estrogenic activities.
Gianni Sagratini, Gulzhan Khamitova, Simone Angeloni, Massimo Ricciutelli, Giovanni Caprioli, Manuela Cortese, Luciano Navarini, Sauro Vittori.   +7 more
core   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

Phytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi, LuLu Zhang, Lan Yan, Qi Geng, Li Li, Xiaojuan He, Ning Zhao, Yong Tan, Xiaomeng Zhang, Cheng Lu   +9 more
wiley   +1 more source

Schisandrin C Targets PPARγ to Induce Ferroptosis in Colorectal Cancer Cells and Promote M1 Macrophage Polarization

Phytotherapy Research, EarlyView.
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei, Hong‐Ping Wen, Jian‐Bo Song, Jin‐Fang Xu, Hong‐Rui Guo   +4 more
wiley   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Biosynthesis of antimalarial lignans from Holostylis reniformis

, 2009
Holostylis reniformis biosynthesizes 8-8' linked lignans without 9,9'-oxygenation. To elucidate the biosynthetic pathways to these lignans, the reputed precursors [U-(14)C]phenylalanine, [9-(3)H(1)]coniferyl alcohol, and [9-(3)H(1)]isoeugenol were ...
Messiano, Gisele B. [UNESP], Nascimento, Isabele Rodrigues, da Silva, Tito [UNESP], da Silva, Tito, Nascimento, Isabele Rodrigues [UNESP], Messiano, Gisele B., Lopes, Lucia Maria Xavier [UNESP], Lopes, Lucia Maria Xavier   +7 more
core   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Higher usual dietary intake of phytoestrogens is associated with lower aortic stiffness in postmenopausal women [PDF]

, 2002
Objective¿ Phytoestrogens have been postulated to protect against cardiovascular diseases, but few studies have focused on the effect of Western dietary phytoestrogen intake.
Pijpelink, A, Bots, ML (Michiel), Grobbee, D.E., Lamberts, S.W.J., Schouw, Y.T., van der, Peeters, P.H.M., van der Schouw, YT, Bots, M.L., van Staveren, W.A., Peeters, PHM, Pijpe, A., van der Schouw, Y.T., Grobbee, DE, van Staveren, WA, Staveren, W.A., van, Lebrun, CEI (Corinne), Lebrun, C.E.I.   +16 more
core   +2 more sources

Development of a New Analytical Method to Quantify Lignans in Coffee by HPLC-MS/MS.

, 2017
A new analytical method to quantify three lignans in espresso coffee have been developed and validated by using HPLC-MS/MS Triple Quadrupole. Different extraction methods (acidic and enzymatic hydrolisis) have been tested and the best extraction process ...
Gulzhan Kamithova, Gianni Sagratini, Sauro Vittori, Massimo Ricciutelli, ANGELONI, Simone, Giovanni Caprioli, Manuela Cortese, Luciano Navarini   +7 more
core   +1 more source