Results 91 to 100 of about 1,540,370 (339)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Parameter Estimation in Semi-Linear Models Using a Maximal Invariant Likelihood Function [PDF]

open access: yes
In this paper, we consider the problem of estimation of semi-linear regression models. Using invariance arguments, Bhowmik and King (2001) have derived the probability density functions of the maximal invariant statistic for the nonlinear component of ...
Jahar L. Bhowmik, Maxwell L. King
core  

To P or not to P: on the evidential nature of P-values and their place in scientific inference [PDF]

open access: yes, 2013
The customary use of P-values in scientific research has been attacked as being ill-conceived, and the utility of P-values has been derided. This paper reviews common misconceptions about P-values and their alleged deficits as indices of experimental ...
Lew, Michael J.
core  

Interval Estimation from the Likelihood Function

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1971
Summary During the last few years, several authors have devoted attention to both old and new methods of making inferences from likelihood functions. In this paper we study the properties of interval estimates which are obtained by drawing a horizontal line across the graph of the likelihood function.
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Semiparametric Estimation and Inference in Multinomial Choice Models [PDF]

open access: yes
The purpose of this paper is to incorporate semiparametric alternatives to maximum likelihood estimation and inference in the context of unordered multinomial response data when in practice there is often insufficient information to specify the ...
Cardell, N. Scott   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Maintaining symmetry of simulated likelihood functions [PDF]

open access: yes
This paper suggests solutions to two different types of simulation errors related to Quasi-Monte Carlo integration. Likelihood functions which depend on standard deviations of mixed parameters are symmetric in nature.
Laura Mørch Andersen
core  

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